methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate

Base Information

• Chemical Name: methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate
• CAS No.: 1206907-39-2
• Molecular Formula: C₁₅H₁₁N₃O₄S
• Molecular Weight: 329.336
• Mol file: 1206907-39-2.mol

Synonyms:methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate

Chemical Property of methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate

There total 1 articles about methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-nitrophenyl bromide (577-19-5) + methyl 3-amino-thieno[3,2-b]pyridine-2-carboxylate (111042-90-1) → methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate (1206907-39-2)

Guidance literature:

With palladium diacetate; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 120 ℃; for 2h;

DOI:10.1016/j.tetlet.2009.10.138

Reference yield: 95.0%

methyl 3-(2-nitrophenylamino)thieno[3,2-b]pyridine-2-carboxylate (1206907-39-2) → methyl 3-(2-aminophenylamino)thieno[3,2-b]pyridine-2-carboxylatete (1206907-41-6)

Guidance literature:

With iron; ammonium chloride; In tetrahydrofuran; ethanol; water; at 80 ℃; for 2h;

DOI:10.1016/j.tetlet.2009.10.138

upstream raw materials:

2-nitrophenyl bromide

methyl 3-amino-thieno[3,2-b]pyridine-2-carboxylate

Downstream raw materials:

methyl 3-(2-aminophenylamino)thieno[3,2-b]pyridine-2-carboxylatete