Ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

Base Information

Chemical Name:Ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate
CAS No.:56003-06-6
Molecular Formula:C₁₃H₁₉NO₄
Molecular Weight:253.298
Hs Code.:
DSSTox Substance ID:DTXSID60510534
Nikkaji Number:J3.019.749F

Synonyms:ETHYL 3-AMINO-2-(3,4-DIMETHOXYPHENYL)PROPANOATE;56003-06-6;SCHEMBL5743088;DTXSID60510534;SVBYEXVSRYCLDO-UHFFFAOYSA-N;SB82042;ETHYL3-AMINO-2-(3,4-DIMETHOXYPHENYL)PROPANOATE;3-amino-2-(3,4-dimethoxy-phenyl)-propionic acid ethyl ester

Suppliers and Price of Ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:253.13140809
Heavy Atom Count:18
Complexity:259

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(CN)C1=CC(=C(C=C1)OC)OC

Technology Process of Ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

There total 4 articles about Ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 36848-69-8
ethyl 2-cyano-2-(3,4-dimethoxyphenyl)acetate

: 56003-06-6
ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

Guidance literature:: With hydrogen; In ethanol; at 20 ℃;
DOI:10.1021/ol202565j

Reference yield:

: 2859-78-1
4-Bromoveratrole

: 105-56-6
ethyl 2-cyanoacetate

: 56003-06-6
ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / Inert atmosphere

1.2: 60 °C / Inert atmosphere

2.1: hydrogen / ethanol / 20 °C

With hydrogen; sodium hydride; In tetrahydrofuran; ethanol;
DOI:10.1021/ol202565j

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 56003-06-6
ethyl 3-amino-2-(3,4-dimethoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium / ethanol; toluene

1.2: 80 °C

2.1: hydrogenchloride; palladium on activated charcoal; hydrogen / ethanol / 2585.81 Torr

With hydrogenchloride; palladium on activated charcoal; hydrogen; sodium; In ethanol; toluene;
DOI:10.1016/j.bmcl.2011.09.009