4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide

Base Information

• Chemical Name: 4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide
• CAS No.: 1373317-07-7
• Molecular Formula: Br*C₃₂H₃₃NO₆P
• Molecular Weight: 638.495
• Mol file: 1373317-07-7.mol

Synonyms:4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide

Chemical Property of 4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide

There total 1 articles about 4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

tris(2-(methoxymethoxy)phenyl)phosphine (124629-80-7) + 4-cyanobenzyl bromide (17201-43-3) → 4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide (1373317-07-7)

Guidance literature:

With sodium hydrogencarbonate; In acetonitrile; at 80 ℃; for 0.166667h;

DOI:10.1021/ic300030b

Reference yield: 50.0%

2,6-di(1H-pyrazol-1-yl)isonicotinaldehyde + 4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide (1373317-07-7) → (Z)-2,6-di(1H-pyrazol-1-yl)-4-(4-cyanostyryl)pyridine (1373317-01-1) + (E)-2,6-di(1H-pyrazol-1-yl)-4-(4-cyanostyryl)pyridine (1373317-02-2)

Guidance literature:

4-cyanobenzyltris(2-(methoxymethoxy)phenyl)phosphonium bromide; With n-butyllithium; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;

2,6-di(1H-pyrazol-1-yl)isonicotinaldehyde; In tetrahydrofuran; at -78 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ic300030b

upstream raw materials:

tris(2-(methoxymethoxy)phenyl)phosphine

4-cyanobenzyl bromide

Downstream raw materials:

(Z)-2,6-di(1H-pyrazol-1-yl)-4-(4-cyanostyryl)pyridine

(E)-2,6-di(1H-pyrazol-1-yl)-4-(4-cyanostyryl)pyridine