2H-Pyran-3(6H)-one,2-[[(3b,20S)-17,20-dihydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-

Base Information

• Chemical Name: 2H-Pyran-3(6H)-one,2-[[(3b,20S)-17,20-dihydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-
• CAS No.: 112899-63-5
• Molecular Formula: C₂₈H₄₂O₆
• Molecular Weight: 474.638
• Mol file: 112899-63-5.mol

Synonyms:Pregnane,2H-pyran-3(6H)-one deriv.; Periplocogenin

Chemical Property of 2H-Pyran-3(6H)-one,2-[[(3b,20S)-17,20-dihydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-

Chemical Property:

Purity/Quality:

98.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2H-Pyran-3(6H)-one,2-[[(3b,20S)-17,20-dihydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl-

There total 10 articles about 2H-Pyran-3(6H)-one,2-[[(3b,20S)-17,20-dihydroxypregn-5-en-3-yl]oxy]-4-methoxy-6-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

periplocoside A (114828-46-5) → 3β-O-(4',6'-dideoxy-3'-O-methyl-Δ3'-D-2'-hexosulosyl)-Δ5-pregnene-3β,17α,20(S)-triol (112899-63-5) + Δ5-pregnene-3β,17α,20(S)-triol 3-O-(4',6'-dideoxy-3'-O-methyl-Δ3'-D-2'-hexosuloside) 20-O-(3'',4''-methylenedioxy-β-D-canaropyranosyde) (116728-48-4) + 2-O-acetyl-β-D-digitalopyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-oleandronic-δ-lactone (110764-09-5) + Δ5-pregnene-3β,17α,20(S)-triol 3-O-(4',6'-dideoxy-3'-O-methyl-Δ3'-D-2'-hexosuloside) 20-O-(3''-O-methoxymethyl-β-D-canaropyranosyde) (116709-67-2)

Guidance literature:

With sulfuric acid; In methanol; for 0.5h; Further byproducts given; Ambient temperature;

DOI:10.1248/cpb.36.2084

Reference yield:

periplocoside A (114828-46-5) → 3β-O-(4',6'-dideoxy-3'-O-methyl-Δ3'-D-2'-hexosulosyl)-Δ5-pregnene-3β,17α,20(S)-triol (112899-63-5) + methyl 2-O-acetyl-β-D-digitalopyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-cymaropyranoside (116709-68-3) + 2-O-acetyl-β-D-digitalopyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-cymaropyranosyl(1->4)-β-D-oleandronic-δ-lactone (110764-09-5) + Δ5-pregnene-3β,17α,20(S)-triol 3-O-(4',6'-dideoxy-3'-O-methyl-Δ3'-D-2'-hexosuloside) 20-O-(3''-O-methoxymethyl-β-D-canaropyranosyde) (116709-67-2)

Guidance literature:

With sulfuric acid; In methanol; for 0.5h; Further byproducts given; Ambient temperature;

DOI:10.1248/cpb.36.2084

Reference yield:

periplocoside A (114828-46-5) → 2-O-acetyl-β-D-digitalopyranosyl(1-> 4)-β-D-cymaropyranoside (23819-23-0) + 3β-O-(4',6'-dideoxy-3'-O-methyl-Δ3'-D-2'-hexosulosyl)-Δ5-pregnene-3β,17α,20(S)-triol (112899-63-5)

Guidance literature:

With sulfuric acid; In methanol; water; at 80 ℃; for 1h;

DOI:10.1248/cpb.36.982

upstream raw materials:

methanol

periplocoside A

Δ⁵-pregnene 3β,17α,20(S)-triol 20-O-β-D-digitalopyranosyl-(1->4)-β-D-cymaropyranosyl-(1->4)-β-D-canoropyranosyl-(1->4)-β-D-digitoxopyranosyl-(1->5)-3,7-dideoxy-4-O-methyl-α-D-gluco-2-heptulopyranosyl-(2-4)-dideoxy-(1->3)-β-D-canaropyranoside

Δ⁵-pregnene-3β,17α,20(S)-triol 20-O-(β-D-digitalopyranosyl-(1->4)-β-D-cymaropyranosyl-(1->4)-β-D-cymaropyranosyl-(1->4)-β-D-cymaropyranosyl-(1->5)-3,7-dideoxy-4-O-methyl-α-D-gluco-2-heptulopyranosyl-(2-4)-dideoxy-(1->3)-β-D-canaropyranoside)