5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester

Base Information

Chemical Name:5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester
CAS No.:1189360-30-2
Molecular Formula:C₁₅H₁₂F₃NO₃
Molecular Weight:311.26
Hs Code.:

Synonyms:5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester

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Chemical Property of 5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester

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Technology Process of 5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester

There total 1 articles about 5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 52679-09-1
[[3-(ethoxycarbonyl)-5-isoxazolyl]methyl]triphenylphosphonium bromide

: 1189360-30-2
5-[(E)-2-(4-trifluoromethylphenyl)ethenyl]-3-isoxazolecarboxylic acid ethyl ester

Guidance literature:: [[3-(ethoxycarbonyl)-5-isoxazolyl]methyl]triphenylphosphonium bromide; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃;

4-Trifluoromethylbenzaldehyde; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1021/jm900513a