2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide

Base Information

• Chemical Name: 2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide
• CAS No.: 1158098-76-0
• Molecular Formula: C₁₄H₁₈N₂O₂S
• Molecular Weight: 278.375
• Mol file: 1158098-76-0.mol

Synonyms:2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide

Chemical Property of 2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide

There total 1 articles about 2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(±)-2-methyl-N-(oxetan-3-ylidene)propane-2-sulfinamide (1158098-73-7) + 4-bromobenzenecarbonitrile (623-00-7) → 2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide (1158098-76-0)

Guidance literature:

(±)-2-methyl-N-(oxetan-3-ylidene)propane-2-sulfinamide; 4-bromobenzenecarbonitrile; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h;

With water; sodium hydrogencarbonate; In tetrahydrofuran; hexane;

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + 2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide (1158098-76-0) → [3-(4-cyano-phenyl)-oxetan-3-yl]-carbamic acid tert-butyl ester (1158098-77-1)

Guidance literature:

2-methyl-propane-2-sulfinic acid [3-(4-cyano-phenyl)-oxetan-3-yl]-amide; With hydrogenchloride; In diethyl ether; dichloromethane; cyclohexane; at 20 ℃; for 0.666667h;

di-tert-butyl dicarbonate; With sodium hydroxide; dmap; In 1,4-dioxane; water; at 20 ℃; for 16h;

upstream raw materials:

(±)-2-methyl-N-(oxetan-3-ylidene)propane-2-sulfinamide

4-bromobenzenecarbonitrile

Downstream raw materials:

[3-(4-cyano-phenyl)-oxetan-3-yl]-carbamic acid tert-butyl ester