2-METHOXY-5,5-DIMETHYL-1,3-DIOXANE

Base Information

• Chemical Name: 2-METHOXY-5,5-DIMETHYL-1,3-DIOXANE
• CAS No.: 78319-58-1
• Molecular Formula: C7H14 O3
• Molecular Weight: 0
• Hs Code.: 2934999090
• Mol file: 78319-58-1.mol

Synonyms:2-Methoxy-5,5-dimethyl-1,3-dioxane

Chemical Property of 2-METHOXY-5,5-DIMETHYL-1,3-DIOXANE

Chemical Property:

• Vapor Pressure: 2.47mmHg at 25°C
• Boiling Point: 165.3°C at 760 mmHg
• Flash Point: 51.4°C
• PSA: 27.69000
• Density: 1g/cm³
• LogP: 0.98940

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHOXY-5,5-DIMETHYL-1,3-DIOXANE

There total 1 articles about 2-METHOXY-5,5-DIMETHYL-1,3-DIOXANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,2-Dimethyl-1,3-propanediol (126-30-7) + trimethyl orthoformate (149-73-5) → 2-methoxy-5,5-dimethyl-1,3-dioxane (78319-58-1)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 20 ℃;

DOI:10.1039/c5cc00644a

Reference yield: 92.0%

2-methoxy-5,5-dimethyl-1,3-dioxane (78319-58-1) + 1-(Trimethylsilyloxy)cyclohexene (6651-36-1) → 2-(5,5-Dimethyl-1,3-dioxan-2-yl)cyclohexanon (99601-21-5)

Guidance literature:

With zinc(II) chloride; In diethyl ether; dichloromethane; for 1h; Ambient temperature;

Reference yield: 67.0%

2-methoxy-5,5-dimethyl-1,3-dioxane (78319-58-1) + 1-styrenyloxytrimethylsilane (13735-81-4) → 2-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-phenylethanon (99601-08-8)

Guidance literature:

With zinc(II) chloride; In diethyl ether; dichloromethane; for 1h; Ambient temperature;

upstream raw materials:

2,2-Dimethyl-1,3-propanediol

trimethyl orthoformate

Downstream raw materials:

2-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-phenylethanon

2-(5,5-Dimethyl-1,3-dioxan-2-yl)cyclohexanon

Refernces

• 1、 Chen, Shuai,Fu, Hao,Gao, Hui,Liu, Bingqing,Sun, Wenfang,Zhang, Yongxin. "Construction of an iridium(iii)-complex-loaded MOF nanoplatform mediated with a dual-responsive polycationic polymer for photodynamic therapy and cell imaging". . p. 762 - 765. Retrieved 2020.
• 2、 Kelly,Chandrakumar,Cutting,et al.. "Synthesis of the dioxabicyclononane unit of tirandamycin". . p. 2173 - 2176. Retrieved 2007/10/02.