2-Styrylbenzothiazole

Base Information

• Chemical Name: 2-Styrylbenzothiazole
• CAS No.: 1483-30-3
• Molecular Formula: C₁₅H₁₁NS
• Molecular Weight: 237.325
• NSC Number: 142140
• Nikkaji Number: J481.122D,J84.895F
• Mol file: 1483-30-3.mol

Synonyms:2-styrylbenzothiazole

Chemical Property of 2-Styrylbenzothiazole

Chemical Property:

• Vapor Pressure: 1.48E-06mmHg at 25°C
• Boiling Point: 410°Cat760mmHg
• Flash Point: 206.5°C
• PSA: 41.13000
• Density: 1.252g/cm³
• LogP: 4.46670
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 237.06122053
• Heavy Atom Count: 17
• Complexity: 270

Purity/Quality:

99% ^*data from raw suppliers

2-(2-PHENYLETHENYL)BENZOTHIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC2=NC3=CC=CC=C3S2
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/C2=NC3=CC=CC=C3S2

Technology Process of 2-Styrylbenzothiazole

There total 23 articles about 2-Styrylbenzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-phenyl-propenal (104-55-2) + 2-amino-benzenethiol (137-07-5) → 2-styrylbenzothiazole (1483-30-3,59066-61-4,104505-71-7)

Guidance literature:

With Ag₂CO₃/celite; In ethanol; at 70 ℃; for 3h;

DOI:10.1007/s13738-015-0592-1

Reference yield: 85.0%

3-phenyl-propenal (104-55-2) + 2-Aminophenyl disulfide (1141-88-4) → 2-styrylbenzothiazole (1483-30-3,59066-61-4,104505-71-7)

Guidance literature:

With oxygen; In water; for 4h; Catalytic behavior; Reflux; Green chemistry;

DOI:10.1039/c5ra14894d

Reference yield: 78.0%

4-methoxy-aniline (104-94-9) + 3-phenyl-propenal (104-55-2) + 2-amino-benzenethiol (137-07-5) → 2-styrylbenzothiazole (1483-30-3,59066-61-4,104505-71-7) + N-cinnamyl-4-methoxybenzenamine (22774-93-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;

DOI:10.1055/s-0030-1260539

upstream raw materials:

2-Methylbenzothiazole

benzaldehyde

cinnamoyl chloride

2-amino-benzenethiol

Downstream raw materials:

2-(2-phenylethyl)-1,3-benzothiazole

4-Benzothiazol-2-yl-1,2,3-triphenyl-butan-1-one

2-(3-Benzothiazol-2-yl-1,2-diphenyl-propyl)-benzooxazole

C₂₉H₂₂N₂S₂

Refernces

• 1、 Abdelrasoul, Amira,Ghorashi, Nadia,Moradi, Reza,Rostami, Amin,Shokri, Zahra. "Aerobic oxidative synthesis of quinazolinones and benzothiazoles in the presence of laccase/DDQ as a bioinspired cooperative catalytic system under mild conditions". . p. 14254 - 14261. Retrieved 2020/04/23.
• 2、 Dhopte, Kiran B.,Zambare, Rahul S.,Patwardhan, Anand V.,Nemade, Parag R.. "Role of graphene oxide as a heterogeneous acid catalyst and benign oxidant for synthesis of benzimidazoles and benzothiazoles". . p. 8164 - 8172. Retrieved 2016/02/05.