Technology Process of C49H53N5O10
There total 10 articles about C49H53N5O10 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
silver cyanide;
In
toluene;
at 70 ℃;
for 3h;
DOI:10.1021/ol100135a
- Guidance literature:
-
Multi-step reaction with 6 steps
1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
2: potassium carbonate / dichloromethane / 13.5 h / 20 °C / Inert atmosphere
3: tetrakis(triphenylphosphine) palladium(0); N-methylaniline / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
4: oxalyl dichloride / dichloromethane / 0 - 20 °C / Inert atmosphere
5: sodium hydrogencarbonate / dichloromethane / 2 h / 20 °C / Inert atmosphere
6: silver cyanide / benzene / 2 h / Reflux; Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); silver cyanide; oxalyl dichloride; sodium hydrogencarbonate; potassium carbonate; N-ethyl-N,N-diisopropylamine; N-methylaniline;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ol201912w
- Guidance literature:
-
Multi-step reaction with 3 steps
1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
2: sodium hydrogencarbonate / dichloromethane / 2 h / 20 °C / Inert atmosphere
3: silver cyanide / benzene / 2 h / Reflux; Inert atmosphere
With
silver cyanide; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ol201912w
