5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one

Base Information

Chemical Name:5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one
CAS No.:17537-76-7
Molecular Formula:C₁₃H₁₀N₂O₂S
Molecular Weight:258.301
Hs Code.:
European Community (EC) Number:819-903-3
ChEMBL ID:CHEMBL1369654
Mol file:17537-76-7.mol

Synonyms:5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one;17537-76-7;5-(4-methoxyphenyl)-3H-thieno[2,3-d]pyrimidin-4-one;CBMicro_036118;Cambridge id 5895295;MLS000715780;SCHEMBL2251842;5-(4-methoxyphenyl)thieno[2,3-d]pyrimidin-4(3H)-one;CHEMBL1369654;HMS2656J14;STL039877;AKOS000676108;AKOS005693798;CCG-125277;SMR000277297;BIM-0036151.P001;CS-0236470;EN300-17109;AB00100379-01;5-(4-methoxyphenyl)thieno[2,3-d]pyrimidin-4-ol;SR-01000427984;SR-01000427984-1;Z56883728;F0745-0338

Suppliers and Price of 5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-(4-Methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one
500mg
$ 289.00

AK Scientific
5-(4-Methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one
100mg
$ 172.00

Total 6 raw suppliers

Chemical Property of 5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one

Chemical Property:

Boiling Point:487.9±40.0 °C(Predicted)
PKA:9.58±0.20(Predicted)
Density:1.40±0.1 g/cm3(Predicted)
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:258.04629874
Heavy Atom Count:18
Complexity:353

Purity/Quality:

99%, ^*data from raw suppliers

5-(4-Methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CSC3=C2C(=O)NC=N3

Technology Process of 5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one

There total 8 articles about 5-(4-methoxyphenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 15854-11-2
ethyl 2-amino-4-(4'-methoxyphenyl) thiophene-3-carboxylate

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 17537-76-7
5-(4-methoxyphenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: at 180 ℃; for 18h;
DOI:10.1021/acs.jmedchem.8b01391

Reference yield:

: 15854-11-2
ethyl 2-amino-4-(4'-methoxyphenyl) thiophene-3-carboxylate

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 17537-76-7
5-(4-methoxy-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one

Guidance literature:: With ammonium formate; at 150 ℃;
DOI:10.2174/1570180811666140122003044

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 17537-76-7
5-(4-methoxy-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 0.5 h / 60 °C

1.2: 0.08 h / 60 °C

1.3: 20 - 60 °C

2.1: ammonium formate / 150 °C

With ammonium formate; In ethanol;
DOI:10.2174/1570180811666140122003044