1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Base Information

Chemical Name:1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline
CAS No.:1228954-24-2
Molecular Formula:C₃₀H₂₃F₂N₅O₂S
Molecular Weight:555.608
Hs Code.:

Synonyms:1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Suppliers and Price of 1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

There total 3 articles about 1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1228954-13-9
(E)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-2-propen-1-one

: 4392-54-5
4-aminosulfonylphenylhydrazine

: 1228954-24-2
1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Guidance literature:: With hydrogenchloride; In water; at 75 ℃;
DOI:10.1016/j.ejmech.2018.01.082

Reference yield: 58.0%

: 1228954-13-9
(E)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-2-propen-1-one

: 17852-52-7,27918-19-0
4-hydrazinobenzene-1-sulfonamide hydrochloride

: 1228954-24-2
1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Guidance literature:: With acetic acid; In ethanol; Reflux;
DOI:10.1016/j.ejmech.2010.01.059

Reference yield:

: 352-06-7
1-(4-fluorobenzylidene)-2-phenylhydrazine

: 1228954-24-2
1-(4-aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(3-(4-fluorophenyl)-1-phenylpyrazol-4-yl)-2-pyrazoline

Guidance literature:: Multi-step reaction with 3 steps

1.1: trichlorophosphate / 0.25 h

1.2: 5 h / 75 - 80 °C

2.1: sodium hydroxide / Reflux

3.1: hydrogenchloride / water / 75 °C

With hydrogenchloride; sodium hydroxide; trichlorophosphate; In water; 2.1: |Claisen-Schmidt Condensation;
DOI:10.1016/j.ejmech.2018.01.082