(E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

Base Information

Chemical Name:(E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime
CAS No.:1311378-40-1
Molecular Formula:C₂₃H₂₂F₃NO
Molecular Weight:385.429
Hs Code.:

Synonyms:(E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

Suppliers and Price of (E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

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Technology Process of (E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

There total 3 articles about (E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 872885-05-7,128812-16-8
1-phenyl-3-cyclohexyl-prop-2-yn-1-ol

: 1311378-40-1
(E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

Guidance literature:: Multi-step reaction with 3 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

2: hydrazine hydrate / tetrahydrofuran / 1 h / 20 °C

3: tetrahydrofuran / 2 h / 65 °C

With di-isopropyl azodicarboxylate; hydrazine hydrate; triphenylphosphine; In tetrahydrofuran; 1: Mitsunobu reaction;
DOI:10.1055/s-0031-1290819

Reference yield:

: C₂₃H₂₁NO₃

: 1311378-40-1
(E)-4-(trifluoromethyl)benzaldehyde O-[3-cyclohexyl-1-phenylprop-2-yn-1-yl]oxime

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / tetrahydrofuran / 1 h / 20 °C

2: tetrahydrofuran / 2 h / 65 °C

With hydrazine hydrate; In tetrahydrofuran;
DOI:10.1055/s-0031-1290819