(2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Base Information

Chemical Name:(2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester
CAS No.:489426-12-2
Molecular Formula:C₂₆H₄₃NO₇Si
Molecular Weight:509.715
Hs Code.:

Synonyms:(2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Suppliers and Price of (2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

There total 5 articles about (2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 489426-30-4
ethyl (3S)-amino-6-(tert-butyldimethylsilanyloxy)hexanoate

: 489426-11-1
4-(trifluoromethanesulfonyloxy)isophthalic acid diethyl ester

: 489426-12-2
(2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Guidance literature:: With triethylamine; In acetonitrile; at 100 ℃; for 12h;
DOI:10.1021/jo026125z

Reference yield:

: 245496-20-2
Ethyl (3S)-3-{N-benzyl-N-[(S)-1-phenylethyl]amino}-6-benzyloxyhexanoate

: 489426-12-2
(2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂; hydrochloric acid / 10percent Pd/C / ethanol; H₂O / 14 h / 50 °C / 38002.6 Torr

2: 80 percent / triethylamine / CH₂Cl₂ / 20 °C

3: 72 percent / triethylamine / acetonitrile / 12 h / 100 °C

With hydrogenchloride; hydrogen; triethylamine; 10percent Pd/C; In ethanol; dichloromethane; water; acetonitrile;
DOI:10.1021/jo026125z

Reference yield:

: 5985-25-1
4-hydroxy-1,3-benzenedicarboxylic acid diethyl ester

: 489426-12-2
(2'S)-4-[5'-(tert-butyldimethylsilanyloxy)-1'-ethoxycarbonylpent-2'-yl]aminoisophthalic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / triethylamine / CH₂Cl₂ / 0.5 h

2: 72 percent / triethylamine / acetonitrile / 12 h / 100 °C

With triethylamine; In dichloromethane; acetonitrile;
DOI:10.1021/jo026125z