1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime

Base Information

• Chemical Name: 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime
• CAS No.: 84736-63-0
• Molecular Formula: C₁₈H₁₉Cl₂NO₂S
• Molecular Weight: 384.326
• Mol file: 84736-63-0.mol

Synonyms:1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime

Chemical Property of 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime

There total 1 articles about 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-methyl p-tolyl sulfoxide (1519-39-7) + 3,5-Dichloro-2,4,6-trimethyl-benzonitrile N-oxide (13456-86-5) → 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime (84736-76-5) + 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime (84736-63-0)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, hexane, -78 -> -20 deg C, 2.) -78 deg C, 30 min;

DOI:10.1055/s-1982-30001

Reference yield: 49.0%

benzyl bromide (100-39-0) + 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone oxime (84736-63-0) → 1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone O-benzyl-oxime (84736-67-4)

Guidance literature:

With sodium hydroxide; benzyltriethylammonium bromide; In dichloromethane; for 48h; Ambient temperature;

DOI:10.1055/s-1982-30001

upstream raw materials:

(R)-methyl p-tolyl sulfoxide

3,5-Dichloro-2,4,6-trimethyl-benzonitrile N-oxide

Downstream raw materials:

1-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-2-((R)-toluene-4-sulfinyl)-ethanone O-benzyl-oxime