4-hydroxy-3-(2-propenyloxy)benzaldehyde

Base Information

• Chemical Name: 4-hydroxy-3-(2-propenyloxy)benzaldehyde
• CAS No.: 52507-49-0
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.188
• Mol file: 52507-49-0.mol

Synonyms:4-hydroxy-3-(2-propenyloxy)benzaldehyde

Chemical Property of 4-hydroxy-3-(2-propenyloxy)benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-hydroxy-3-(2-propenyloxy)benzaldehyde

There total 12 articles about 4-hydroxy-3-(2-propenyloxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3,4-diallyloxybenzaldehyde (71186-67-9) → 4-hydroxy-3-(2-propenyloxy)benzaldehyde (52507-49-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tri-n-butyl-tin hydride; In dichloromethane; at 23 ℃; for 1.5h;

DOI:10.1021/ja0483037

Reference yield: 65.0%

3,4-diallyloxybenzaldehyde (71186-67-9) → 4-hydroxy-3-(2-propenyloxy)benzaldehyde (52507-49-0) + 3-hydroxy-4-(2-propenyloxy)benzaldehyde (79822-65-4)

Guidance literature:

With methanol; potassium hydroxide; palladium on activated charcoal; at 20 ℃; for 18h;

DOI:10.1248/cpb.54.1299

Reference yield: 63.0%

allyl bromide (106-95-6) + 3,4-dihydroxybenzaldehyde (139-85-5) → 4-hydroxy-3-(2-propenyloxy)benzaldehyde (52507-49-0)

Guidance literature:

3,4-dihydroxybenzaldehyde; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃;

allyl bromide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;

With hydrogenchloride; In water; N,N-dimethyl-formamide; mineral oil;

DOI:10.1002/anie.200902840

upstream raw materials:

chloral

2-allyloxyphenol

allyl bromide

3,4-dihydroxybenzaldehyde

Downstream raw materials:

3,4-dihydroxy-2-(2-propenyl)benzaldehyde

3-allyloxy-4-hydroxybenzyl alcohol

[3-allyloxy-4-(3-bromopropoxy)phenyl]methanol

[3-allyloxy-4-(2-bromo-[D₄]ethoxy)phenyl]methanol