(E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene

Base Information

• Chemical Name: (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene
• CAS No.: 1095091-89-6
• Molecular Formula: C₁₉H₂₂O
• Molecular Weight: 266.383
• Mol file: 1095091-89-6.mol

Synonyms:(E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene

Chemical Property of (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene

There total 4 articles about (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

4-methoxyphenylboronic acid (5720-07-0) + 4-acetoxy-6-phenylhex-2-ene (147330-92-5) → (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene (1095091-89-6) + (E)-5-(4-methoxylphenyl)-1-phenyl-3-hexene

Guidance literature:

With silver hexafluoroantimonate; 1,10-Phenanthroline; palladium diacetate; In 1,2-dichloro-ethane; at 60 ℃; for 12h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ja808673n

Reference yield: 57.0%

4-methoxyphenylboronic acid (5720-07-0) + 4-acetoxy-6-phenylhex-2-ene (147330-92-5) → (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene (1095091-89-6)

Guidance literature:

With C₃₆H₃₀N₆O₁₂Pd₂S₂; In 1,2-dichloro-ethane; at 20 - 60 ℃; optical yield given as %de; stereospecific reaction;

DOI:10.1002/asia.201000721

Reference yield: 42.0%

diethyl (Z)-6-phenyl-2-hexen-4-yl phosphate (1215180-93-0) + 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane (213596-33-9) → (E)-5-(4-methoxyphenyl)-1-phenyl-3-hexene (1095091-89-6)

Guidance literature:

With potassium tert-butylate; acetylacetone; copper(l) chloride; In water; acetonitrile; at 80 ℃; for 12h; optical yield given as %de; stereospecific reaction; Inert atmosphere;

DOI:10.1021/ol100841y

upstream raw materials:

4-methoxyphenylboronic acid

4-acetoxy-6-phenylhex-2-ene

diethyl (Z)-6-phenyl-2-hexen-4-yl phosphate

2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane