N-(2-Hydroxypropyl)dibutylamine

Base Information

• Chemical Name: N-(2-Hydroxypropyl)dibutylamine
• CAS No.: 2109-64-0
• Molecular Formula: C₁₁H₂₅NO
• Molecular Weight: 187.326
• European Community (EC) Number: 218-297-2
• NSC Number: 163302
• DSSTox Substance ID: DTXSID601030739
• Nikkaji Number: J50.967A
• Mol file: 2109-64-0.mol

Synonyms:1-Dibutylamino-2-propanol;Dibutylisopropanolamine;1-Dibutylaminopropan-2-ol;Di-n-Butylamino-2-propanol;2-Propanol, 1-(dibutylamino)-;2109-64-0;N-(2-Hydroxypropyl)dibutylamine;1-(Dibutylamino)-2-propanol;2-Propanol, 1-dibutylamino-;N,N-Dibutyl(2-hydroxypropyl)amine;EINECS 218-297-2;NSC 163302;BRN 1741001;N,N-Dibutyl-2-hydroxypropylamine;3-04-00-00759 (Beilstein Handbook Reference);NSC163302;SCHEMBL1009972;1-(N-dibutylamino)-2-propanol;ICMJHPBQTVWCNT-UHFFFAOYSA-;WLN: QY1&1N4&4;DTXSID601030739;AKOS010107180;NSC-163302;LS-122040;FT-0607699

Chemical Property of N-(2-Hydroxypropyl)dibutylamine

Chemical Property:

• Vapor Pressure: 0.00167mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• Boiling Point: 261.3°C at 760 mmHg
• Flash Point: 89.4°C
• PSA: 23.47000
• Density: 0.87g/cm³
• LogP: 2.26940
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 187.193614421
• Heavy Atom Count: 13
• Complexity: 98.3

Purity/Quality:

99% ^*data from raw suppliers

1-Dibutylamino-propan-2-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCN(CCCC)CC(C)O

Technology Process of N-(2-Hydroxypropyl)dibutylamine

There total 4 articles about N-(2-Hydroxypropyl)dibutylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dibutylamine (111-92-2) + methyloxirane (75-56-9,16033-71-9) → N-(2-hydroxypropyl)-dibutylamine (2109-64-0,78679-33-1,78679-34-2)

Guidance literature:

1,3-bis(3,5-bis(trifluoro-ethyl)phenyl)thiourea; In water; at 20 ℃;

DOI:10.1039/b605850g

Reference yield: 39.0%

propylene glycol (57-55-6,63625-56-9) + dibutylamine (111-92-2) → N-(2-hydroxypropyl)-dibutylamine (2109-64-0,78679-33-1,78679-34-2)

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In tetrahydrofuran; at -18 - 80 ℃; for 1h;

DOI:10.1016/0040-4039(95)02046-2

Reference yield:

3-dibutylamino-2-propanethiol (21734-35-0) + methyloxirane (75-56-9,16033-71-9) → N-(2-hydroxypropyl)-dibutylamine (2109-64-0,78679-33-1,78679-34-2) + propylene sulphide (1072-43-1)

Guidance literature:

at 80 ℃; for 34h;

upstream raw materials:

dibutylamine

methyloxirane

3-dibutylamino-2-propanethiol

propylene glycol