(2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide

Base Information

Chemical Name:(2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide
CAS No.:1094537-98-0
Molecular Formula:C₂₂H₂₉NO₂
Molecular Weight:339.478
Hs Code.:

Synonyms:(2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide

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Technology Process of (2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide

There total 1 articles about (2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 4119-41-9
1-iodo-3-phenylpropan

: 159213-03-3
N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N-methylpropionamide

: 1094537-98-0
(2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide

Guidance literature:: N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N-methylpropionamide; With lithium chloride; lithium diisopropyl amide; In tetrahydrofuran; at -78 - 23 ℃; for 1h; Inert atmosphere;

1-iodo-3-phenylpropan; In tetrahydrofuran; at 0 ℃; for 0.75h; Inert atmosphere;
DOI:10.1021/ja808347q

Reference yield: 93.0%

: 1094537-98-0
(2R)-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-2-methyl-5-phenylpentanoic acid methylamide

: 156767-44-1
(+)-(R)-2-Methyl-5-phenyl-1-pentanol

Guidance literature:: With borane-ammonia complex; lithium diisopropyl amide; In tetrahydrofuran; at 23 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ja808347q