Acetamide, N-((dimethylamino)methyl)-

Base Information

• Chemical Name: Acetamide, N-((dimethylamino)methyl)-
• CAS No.: 38221-31-7
• Molecular Formula: C5H12N2O
• Molecular Weight: 116.163
• Hs Code.: 2924199090
• NSC Number: 47173
• UNII: 26SK5552YZ
• DSSTox Substance ID: DTXSID20191601
• Wikidata: Q83064146
• Mol file: 38221-31-7.mol

Synonyms:38221-31-7;Acetamide, N-((dimethylamino)methyl)-;n-[(dimethylamino)methyl]acetamide;N-((Dimethylamino)methyl)acetamide;26SK5552YZ;NSC-47173;ACETAMIDE,N-((DIMETHYLAMINO)METHYL)-;NSC 47173;BRN 2072080;N-Dimethylaminomethyl-acetamid [German];N-Dimethylaminomethyl-acetamid;NSC47173;UNII-26SK5552YZ;SCHEMBL4431672;DTXSID20191601;AKOS006278434

Chemical Property of Acetamide, N-((dimethylamino)methyl)-

Chemical Property:

• Vapor Pressure: 0.0767mmHg at 25°C
• Boiling Point: 227.6°C at 760 mmHg
• Flash Point: 91.5°C
• PSA: 32.34000
• Density: 0.934g/cm³
• LogP: 0.03250
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 116.094963011
• Heavy Atom Count: 8
• Complexity: 80.5

Purity/Quality:

99% ^*data from raw suppliers

N-((DIMETHYLAMINO)METHYL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NCN(C)C

Technology Process of Acetamide, N-((dimethylamino)methyl)-

There total 1 articles about Acetamide, N-((dimethylamino)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(hydroxymethyl)acetamide (625-51-4) + dimethyl amine (124-40-3) → Dimethylaminomethyl-acetamid (38221-31-7)

Guidance literature:

In water;

DOI:10.1002/ardp.19723050606

Reference yield: 62.0%

Dimethylaminomethyl-acetamid (38221-31-7) → Bis<(acetylamino)methyl>dimethylammonium-tetrafluoroborat + N,N-dimethylbenzamide (611-74-5)

Guidance literature:

With tetrafluoroboric acid; benzoyl chloride; In diethyl ether; dichloromethane; at 20 ℃; for 1h;

Reference yield:

Dimethylaminomethyl-acetamid (38221-31-7) → Bis<(acetylamino)methyl>dimethylammoniumchlorid (80179-53-9) + N,N-dimethylbenzamide (611-74-5)

Guidance literature:

With benzoyl chloride; In chloroform-d1; at 20 ℃;

upstream raw materials:

N-(hydroxymethyl)acetamide

dimethyl amine

Downstream raw materials:

Dimethyl-dithiocarbamic acid acetylamino-methyl ester

Bis<(acetylamino)methyl>dimethylammoniumchlorid

N,N-dimethylbenzamide