1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan

Base Information

• Chemical Name: 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan
• CAS No.: 24405-22-9
• Molecular Formula: C₁₂H₂₄O
• Molecular Weight: 184.322
• Mol file: 24405-22-9.mol

Synonyms:1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan

Chemical Property of 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan

There total 5 articles about 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-tert-butyl-1-methylcyclohexanecarboxylate (219812-28-9) → 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan (24405-22-9) + 4-tert-butyl-1-methylcyclohexylmethanol (24405-21-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Heating;

DOI:10.1021/ja9823013

Reference yield:

1-Methyl-trans-4-tert-butylcyclohexanecarboxylic acid (27069-57-4) → 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan (24405-22-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield:

4-tert-butyl-1-methyl-cyclohex-3-enecarboxylic acid (27036-63-1) → 1r-Hydroxymethyl-4t-tert.-butyl-1-methyl-cyclohexan (24405-22-9)

Guidance literature:

Multistep reaction; (i) H₂, PtO₂, EtOH, (ii) LiAlH₄, Et₂O;

upstream raw materials:

4-tert-butyl-1-methyl-cyclohex-3-enecarboxylic acid

1-Methyl-trans-4-tert-butylcyclohexanecarboxylic acid

methyl magnesium iodide

carbon dioxide

Downstream raw materials:

N-(4-tert-Butyl-1-methyl-cyclohexyl)-acetamide

4refH-4-tert.-Butyl-1cis-carbamoyl-1-methylcyclohexan

4refH-4-tert.-Butyl-1cis-acetyl-1-methyl-cyclohexan

4-tert-butyl-1-methylcyclohexanecarbonitrile