Methyl beta-hydroxy-2,3-dimethoxybenzenepropanoate

Base Information

Chemical Name:Methyl beta-hydroxy-2,3-dimethoxybenzenepropanoate
CAS No.:300840-19-1
Molecular Formula:C₁₂H₁₆O₅
Molecular Weight:240.256
Hs Code.:
DSSTox Substance ID:DTXSID901243424

Synonyms:300840-19-1;DTXSID901243424;EN300-1816210;methyl 3-(2,3-dimethoxyphenyl)-3-hydroxypropanoate

Suppliers and Price of Methyl beta-hydroxy-2,3-dimethoxybenzenepropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl beta-hydroxy-2,3-dimethoxybenzenepropanoate

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:240.09977361
Heavy Atom Count:17
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1OC)C(CC(=O)OC)O

Technology Process of Methyl beta-hydroxy-2,3-dimethoxybenzenepropanoate

There total 4 articles about Methyl beta-hydroxy-2,3-dimethoxybenzenepropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 300840-18-0
methyl 3-oxo-3-(2,3-dimethoxyphenyl)propanoate

: 300840-19-1
methyl 3-hydroxy-3-(2,3-dimethoxyphenyl)propanoate

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃; for 1h;
DOI:10.1016/S0040-4020(00)00427-0

Reference yield:

: 1521-38-6
2,3-dimethoxybenzoic acid

: 300840-19-1
methyl 3-hydroxy-3-(2,3-dimethoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 2 h / 0 - 20 °C

2: 655 mg / tetrahydrofuran / 40 h / 20 °C

3: 81 percent / NaBH₄ / methanol / 1 h / 0 °C

With sodium tetrahydroborate; In tetrahydrofuran; methanol; 1: Substitution / 2: Substitution / 3: Reduction;
DOI:10.1016/S0040-4020(00)00427-0

Reference yield:

: 154558-56-2
(2,3-Dimethoxy-phenyl)-imidazol-1-yl-methanone

: 300840-19-1
methyl 3-hydroxy-3-(2,3-dimethoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 655 mg / tetrahydrofuran / 40 h / 20 °C

2: 81 percent / NaBH₄ / methanol / 1 h / 0 °C

With sodium tetrahydroborate; In tetrahydrofuran; methanol; 1: Substitution / 2: Reduction;
DOI:10.1016/S0040-4020(00)00427-0