5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

Base Information

• Chemical Name: 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid
• CAS No.: 234081-82-4
• Molecular Formula: C₅₃H₉₂N₄O₈
• Molecular Weight: 913.335

Synonyms:5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

Chemical Property of 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

There total 9 articles about 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid tert-butyl ester (234081-72-2) → 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid (234081-82-4)

Guidance literature:

With trifluoroacetic acid; In chloroform; at 20 ℃;

DOI:10.1016/S0009-3084(02)00053-1

Reference yield:

hexadecylamine (143-27-1) → 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid (234081-82-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 88 percent / 1-hydroxybenzotriazole hydrate; 2-(1H-benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium*BF₄^(1-); 4-dimethylaminopyridine / CHCl₃; dimethylformamide / 3 h / 20 °C

2: 78 percent / trifluoroacetic acid / CHCl₃ / 2 h / 20 °C

3: 46 percent / 1-hydroxybenzotriazole hydrate; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; 4-dimethylaminopyridine / CH₂Cl₂; dimethylformamide / 5 h / 20 °C

4: 81 percent / trifluoroacetic acid / CHCl₃ / 1 h / 20 °C

5: 59 percent / 1-hydroxybenzotriazole hydrate; 2-(1H-benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium*BF₄^(1-); 4-dimethylaminopyridine / CHCl₃; dimethylformamide / 20 °C

6: 99 percent / trifluoroacetic acid / CHCl₃ / 20 °C

With dmap; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane; chloroform; N,N-dimethyl-formamide;

DOI:10.1016/S0009-3084(02)00053-1

Reference yield:

6-(tert-butoxy)-6-oxohexanoic acid (52221-07-5) → 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid (234081-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 59 percent / 1-hydroxybenzotriazole hydrate; 2-(1H-benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium*BF₄^(1-); 4-dimethylaminopyridine / CHCl₃; dimethylformamide / 20 °C

2: 99 percent / trifluoroacetic acid / CHCl₃ / 20 °C

With dmap; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 1-hydroxybenzotriazol-hydrate; trifluoroacetic acid; In chloroform; N,N-dimethyl-formamide;

DOI:10.1016/S0009-3084(02)00053-1

upstream raw materials:

5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid tert-butyl ester

Adipic acid

hexadecylamine

6-(tert-butoxy)-6-oxohexanoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 234081-82-4 5-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-pentanoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send