4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester

Base Information

Chemical Name:4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester
CAS No.:78756-03-3
Molecular Formula:C15H15N3O3
Molecular Weight:285.302
Hs Code.:
UNII:PP61C9NWB0
DSSTox Substance ID:DTXSID10999991
Nikkaji Number:J23.738H
Wikidata:Q82993331
ChEMBL ID:CHEMBL267665

Synonyms:Ro 14-7437;Ro-14-7437

Suppliers and Price of 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester

Chemical Property:

Vapor Pressure:3.38E-11mmHg at 25°C
Boiling Point:527°C at 760 mmHg
Flash Point:272.5°C
Density:1.33g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:285.11134135
Heavy Atom Count:21
Complexity:428

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C2CN(C(=O)C3=CC=CC=C3N2C=N1)C

Technology Process of 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester

There total 7 articles about 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1350523-27-1
(3-(ethoxycarbonyl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-8-yl)(4-methylphenyl)iodonium tosylate

: 78756-03-3
ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate

: 78755-81-4
flumazenil

: 268566-09-2
Ro 41-8157

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; cesium fluoride; In N,N-dimethyl-formamide; acetonitrile; at 90 ℃; for 2h;
DOI:10.1039/c1ob06277h

Reference yield:

: 1350523-17-9
(3-(ethoxycarbonyl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-8-yl)(phenyl)iodonium tosylate

: 78756-03-3
ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate

: 78755-81-4
flumazenil

: 268566-09-2
Ro 41-8157

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; cesium fluoride; In N,N-dimethyl-formamide; acetonitrile; at 90 ℃; for 2h;
DOI:10.1039/c1ob06277h

Reference yield:

: 1350523-19-1
(3-(ethoxycarbonyl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-8-yl)(2-thiophenyl)iodonium tosylate

: 78756-03-3
ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate

: 78755-81-4
flumazenil

: 268566-09-2
Ro 41-8157

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; cesium fluoride; In N,N-dimethyl-formamide; acetonitrile; at 90 ℃; for 2h;
DOI:10.1039/c1ob06277h