8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

Base Information

Chemical Name:8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester
CAS No.:268566-09-2
Molecular Formula:C15H14IN3O3
Molecular Weight:411.199
Hs Code.:
Nikkaji Number:J1.262.625H
Mol file:268566-09-2.mol

Synonyms:8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester;268566-09-2;ethyl 8-iodo-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate;SCHEMBL15603826;IBE

Suppliers and Price of 8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

Chemical Property:

PSA：64.43000
LogP:2.17710
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:411.00799
Heavy Atom Count:22
Complexity:461

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)I)C

Technology Process of 8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester

There total 6 articles about 8-Iodo-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1350523-27-1
(3-(ethoxycarbonyl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-8-yl)(4-methylphenyl)iodonium tosylate

: 78756-03-3
ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate

: 78755-81-4
flumazenil

: 268566-09-2
Ro 41-8157

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; cesium fluoride; In N,N-dimethyl-formamide; acetonitrile; at 90 ℃; for 2h;
DOI:10.1039/c1ob06277h

Reference yield:

: 1350523-17-9
(3-(ethoxycarbonyl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-8-yl)(phenyl)iodonium tosylate

: 78756-03-3
ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate

: 78755-81-4
flumazenil

: 268566-09-2
Ro 41-8157

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; cesium fluoride; In N,N-dimethyl-formamide; acetonitrile; at 90 ℃; for 2h;
DOI:10.1039/c1ob06277h

Reference yield:

: 1350523-19-1
(3-(ethoxycarbonyl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-8-yl)(2-thiophenyl)iodonium tosylate

: 78756-03-3
ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate

: 78755-81-4
flumazenil

: 268566-09-2
Ro 41-8157

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; cesium fluoride; In N,N-dimethyl-formamide; acetonitrile; at 90 ℃; for 2h;
DOI:10.1039/c1ob06277h