Technology Process of N-ethoxycarbonyl-1-(but-3-enyl)cyclohexylamine
There total 3 articles about N-ethoxycarbonyl-1-(but-3-enyl)cyclohexylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iPr2NLi / tetrahydrofuran / -78 °C
2: 15percent ethanolic KOH / Heating
3: 1) triethylamine, diphenyl azidophosphate, 2) a) dibutyltin diacetate, b) aq. NaOH / 1) benzene, reflux, 3 h, 2) a) reflux, 48 h, b) ethanol, reflux, 0.5 h
With
potassium hydroxide; sodium hydroxide; dibutyltin diacetate; diphenyl phosphoryl azide; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran;
DOI:10.1016/S0040-4020(01)96036-3
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 15percent ethanolic KOH / Heating
2: 1) triethylamine, diphenyl azidophosphate, 2) a) dibutyltin diacetate, b) aq. NaOH / 1) benzene, reflux, 3 h, 2) a) reflux, 48 h, b) ethanol, reflux, 0.5 h
With
potassium hydroxide; sodium hydroxide; dibutyltin diacetate; diphenyl phosphoryl azide; triethylamine;
DOI:10.1016/S0040-4020(01)96036-3
- Guidance literature:
-
With
sodium hydroxide; dibutyltin diacetate; diphenyl phosphoryl azide; triethylamine;
Yield given. Multistep reaction;
1) benzene, reflux, 3 h, 2) a) reflux, 48 h, b) ethanol, reflux, 0.5 h;
DOI:10.1016/S0040-4020(01)96036-3
