Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride

Base Information

Chemical Name:Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride
CAS No.:97127-77-0
Molecular Formula:C₁₉H₂₀BrNO*ClH
Molecular Weight:394.739
Hs Code.:
DSSTox Substance ID:DTXSID30914166

Synonyms:Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride;97127-77-0;2-(p-Bromophenyl)-2-benzylaminocyclohexan-1-one hydrochloride;Cyclohexanone, 2-(4-bromophenyl)-2-((phenylmethyl)amino)-, hydrochloride;C19H20BrNO.ClH;DTXSID30914166;C19-H20-Br-N-O.Cl-H;LS-57278;2-(Benzylamino)-2-(4-bromophenyl)cyclohexan-1-onato--hydrogen chlorido (1/1)

Suppliers and Price of Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride

Chemical Property:

Vapor Pressure:4.54E-09mmHg at 25°C
Boiling Point:471.7°C at 760 mmHg
Flash Point:239.1°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:393.04950
Heavy Atom Count:23
Complexity:372

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(C(=O)C1)(C2=CC=C(C=C2)Br)NCC3=CC=CC=C3.Cl

Technology Process of Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride

There total 5 articles about Cyclohexanone, 2-benzylamino-2-(p-bromophenyl)-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 2-p-bromophenyl-2-benzylaminocyclohexan-1-ol

: 97127-77-0
2-p-bromophenyl-2-benzylaminocyclohexan-1-one hydrochloride

Guidance literature:: With chromium(VI) oxide; hydrogenchloride; acetic acid; In water; at 50 ℃; for 5h;

Reference yield:

: 1605-15-8
1-p-bromophenyl-1,2-epoxycyclohexane

: 97127-77-0
2-p-bromophenyl-2-benzylaminocyclohexan-1-one hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaN₃, AcOH; 2.) LiAlH₄; 3.) CrO₃, glacial AcOH / 1.) EtOH-water, RT, 6 h; 100 deg C, 10 h; 2.) ether, reflux, 5 h; overnight; 3.) H₂O, 50 deg C, 5 h

2: 98 percent / 10 percent NaOH / H₂O / 1 h / 5 °C

3: 91 percent / 1.) LAH; 2.) 20percent NaOH / diethyl ether / 8 h / Heating

4: 36 percent / 1.) CrO₃, glacial AcOH; 2.) HCl in ether / H₂O / 5 h / 50 °C

With chromium(VI) oxide; hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; sodium azide; acetic acid; In diethyl ether; water;

Reference yield:

: 1605-17-0
1-Bromo-4-(1-cyclohexen-1-yl)benzene

: 97127-77-0
2-p-bromophenyl-2-benzylaminocyclohexan-1-one hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: 40.8 percent / Na₂CO₃, peracetic acid / CH₂Cl₂ / 4 h / 0 °C

2: 1.) NaN₃, AcOH; 2.) LiAlH₄; 3.) CrO₃, glacial AcOH / 1.) EtOH-water, RT, 6 h; 100 deg C, 10 h; 2.) ether, reflux, 5 h; overnight; 3.) H₂O, 50 deg C, 5 h

3: 98 percent / 10 percent NaOH / H₂O / 1 h / 5 °C

4: 91 percent / 1.) LAH; 2.) 20percent NaOH / diethyl ether / 8 h / Heating

5: 36 percent / 1.) CrO₃, glacial AcOH; 2.) HCl in ether / H₂O / 5 h / 50 °C

With chromium(VI) oxide; hydrogenchloride; peracetic acid; sodium hydroxide; lithium aluminium tetrahydride; sodium azide; sodium carbonate; acetic acid; In diethyl ether; dichloromethane; water;