1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate
CAS No.:887920-73-2
Molecular Formula:C₃₂H₃₅FN₂O₄
Molecular Weight:530.639
Hs Code.:

Synonyms:1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

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Chemical Property of 1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

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Technology Process of 1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

There total 1 articles about 1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 887920-69-6
1,1-dimethylethyl 4-{[3-({[(3-bromo-4-fluorophenyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

: 87199-16-4
3-Formylphenylboronic acid

: 887920-73-2
1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 150 ℃; for 0.333333h; Irradiation in microwave;

Reference yield: 27.0%

: 887920-73-2
1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate

: 169447-70-5
(S)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester

: N-{[6-fluoro-3'-(1-piperazinylmethyl)-3-biphenylyl]methyl}-3-(4-piperidinylmethyl)benzamide

Guidance literature:: 1,1-dimethylethyl 4-{[3-({[(6-fluoro-3'-formyl-3-biphenylyl)methyl]amino}carbonyl)phenyl]methyl}-1-piperidinecarboxylate; (S)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester; With sodium tris(acetoxy)borohydride; In dichloromethane; for 16h;

With trifluoroacetic acid; In dichloromethane; for 1h;