ETHYL MESITYLACETATE

Base Information

• Chemical Name: ETHYL MESITYLACETATE
• CAS No.: 5460-08-2
• Molecular Formula: C13H18 O2
• Molecular Weight: 206.285
• Hs Code.: 2915900090
• Mol file: 5460-08-2.mol

Synonyms:Aceticacid, mesityl-, ethyl ester (6CI,7CI,8CI); Acetic acid,(2,4,6-trimethylphenyl)-, ethyl ester; Ethyl 2-(2,4,6-trimethylphenyl)ethanoate;NSC 8350

Chemical Property of ETHYL MESITYLACETATE

Chemical Property:

• Vapor Pressure: 0.0023mmHg at 25°C
• Refractive Index: 1.5050
• Boiling Point: 288.7°Cat760mmHg
• Flash Point: 112.6°C
• PSA: 26.30000
• Density: 0.993g/cm³
• LogP: 2.71740

Purity/Quality:

99% ^*data from raw suppliers

Ethyl mesitylacetate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL MESITYLACETATE

There total 15 articles about ETHYL MESITYLACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,4,6-trimethylphenyl bromide (576-83-0) + diethyl malonate (105-53-3) → ethyl 2,4,6-trimethylphenylacetate (5460-08-2)

Guidance literature:

With palladium diacetate; 1,3-bis(alkyl)imidazolium chloride (LHX₅); caesium carbonate; In 1,4-dioxane; at 80 ℃; for 24h;

DOI:10.1016/j.tetlet.2004.06.012

Reference yield: 93.0%

ethyl 2-(2,4,6-trimethylcyclohepta-2,4,6-trien-1-yl)acetate → ethyl 2,4,6-trimethylphenylacetate (5460-08-2)

Guidance literature:

With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; In 2,2,2-trifluoroethanol; acetonitrile; Irradiation;

DOI:10.1002/anie.202000684

Reference yield: 86.0%

ethyl α-(phenylseleno) mesityl acetate (138100-85-3) → ethyl 2,4,6-trimethylphenylacetate (5460-08-2)

Guidance literature:

With tellurium; sodium tetrahydroborate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1080/00397919408011508

upstream raw materials:

ethanol

mesitylacetonitrile

2-mesitylacetic acid

(2,4,6-trimethyl-phenyl)acetyl chloride

Downstream raw materials:

2-(2,4,6-trimethylphenyl)malonic acid diethyl ester

Refernces

• 1、 Benaissa, Idir,Pallova, Lenka,Morantin, Marie-Emilie,Lafitte, Thomas,Huynh, Mathieu,Barthes, Cécile,Vendier, Laure,Lugan, No?l,Bastin, Stéphanie,César, Vincent. "N-Heterocyclic Carbenes as Key Intermediates in the Synthesis of Fused, Mesoionic, Tricyclic Heterocycles". supporting information. p. 13030 - 13036. Retrieved 2019/11/05.
• 2、 Conde, Ana,Sabenya, Gerard,Rodríguez, Mònica,Postils, Verònica,Luis, Josep M.,Díaz-Requejo, M. Mar,Costas, Miquel,Pérez, Pedro J.. "Iron and manganese catalysts for the selective functionalization of arene C(sp2)-H bonds by carbene insertion". supporting information. p. 6530 - 6534. Retrieved 2016/06/01.