C₁₃H₉N₃O₃

Base Information

• Chemical Name: C₁₃H₉N₃O₃
• CAS No.: 1448590-00-8
• Molecular Formula: C₁₃H₉N₃O₃
• Molecular Weight: 255.233
• Mol file: 1448590-00-8.mol

Synonyms:C₁₃H₉N₃O₃

Chemical Property of C₁₃H₉N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₃H₉N₃O₃

There total 1 articles about C₁₃H₉N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethyl-4-nitroisoxazole (1123-49-5) + 4-cyanobenzaldehyde (105-07-7) → C13H9N3O3 (1448590-00-8)

Guidance literature:

With piperidine; In ethanol; at 65 ℃;

DOI:10.1039/c5ob01880c

Reference yield: 86.0%

Ethyl isocyanoacetate (2999-46-4) + C13H9N3O3 (1448590-00-8) → (3R)-3-(4-cyano-phenyl)-2-isocyano-4-(3-methyl-4-nitro-isoxazol-5-yl)-butyric acid ethyl ester

Guidance literature:

With N-(3,5-bis(tert-butyl)benzyl)cinchoninium bromide; potassium carbonate; In toluene; at -20 ℃; for 48h;

DOI:10.1039/c5ob01880c

Reference yield:

C13H9N3O3 (1448590-00-8) + diphenylphosphane (829-85-6) → C25H20N3O3P (1448590-11-1) + C25H20N3O3P

Guidance literature:

With bis(acetonitrile)[(S)-1-[1-(dimethylamino)ethyl]-2-naphthalenyl-C⁽²⁾,N]palladium(II) perchlorate; triethylamine; In chloroform; at -45 ℃; for 1.66667h; Overall yield = 98%; Overall yield = 86.5mg; enantioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/adsc.201300164

upstream raw materials:

3,5-dimethyl-4-nitroisoxazole

4-cyanobenzaldehyde

Downstream raw materials:

C₂₅H₂₀N₃O₃P