Technology Process of 3-phenyl-3-(pyridazin-4-yl)propanoyl azide
There total 6 articles about 3-phenyl-3-(pyridazin-4-yl)propanoyl azide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diphenyl phosphoryl azide; triethylamine;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1.5h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sulfuric acid; silver nitrate; ammonium persulfate / water / 1.5 h / 60 - 90 °C
2.1: selenium(IV) oxide; acetic acid / 1 h / 100 °C
3.1: sodium hydride / tetrahydrofuran / 0.33 h / 0 °C
3.2: 4 h / 0 °C
4.1: benzenesufonyl hydrazide; triethylamine / toluene / 100 °C
5.1: sodium hydroxide; water / methanol
5.2: pH 4-5
6.1: diphenyl phosphoryl azide; triethylamine / N,N-dimethyl-formamide / 1.5 h / 0 - 20 °C
With
selenium(IV) oxide; ammonium persulfate; sulfuric acid; diphenyl phosphoryl azide; water; sodium hydride; silver nitrate; acetic acid; triethylamine; benzenesufonyl hydrazide; sodium hydroxide;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran / 0.33 h / 0 °C
1.2: 4 h / 0 °C
2.1: benzenesufonyl hydrazide; triethylamine / toluene / 100 °C
3.1: sodium hydroxide; water / methanol
3.2: pH 4-5
4.1: diphenyl phosphoryl azide; triethylamine / N,N-dimethyl-formamide / 1.5 h / 0 - 20 °C
With
diphenyl phosphoryl azide; water; sodium hydride; triethylamine; benzenesufonyl hydrazide; sodium hydroxide;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;
