tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane

Base Information

• Chemical Name: tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane
• CAS No.: 351536-27-1
• Molecular Formula: C₁₇H₂₅Cl₃OSi
• Molecular Weight: 379.829
• Mol file: 351536-27-1.mol

Synonyms:tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane

Chemical Property of tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane

There total 5 articles about tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-2-methylcinnamaldehyde (4549-82-0,93614-78-9) → tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane (351536-27-1)

Guidance literature:

Multi-step reaction with 2 steps

1: CCl₃CO₂H / dimethylformamide / 20 °C

2: imidazole / dimethylformamide / 20 °C

With 1H-imidazole; trichloroacetic acid; In N,N-dimethyl-formamide;

DOI:10.1021/jo010068c

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) + 1,1,1-trichloro-4-o-tolyl-but-3-en-2-ol (351536-43-1) → tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane (351536-27-1)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jo010068c

Reference yield:

(E)-3-(2-methylphenyl)acrylic acid (939-57-1,2373-76-4,41397-71-1) → tert-butyl-dimethyl-(3-o-tolyl-1-trichloromethyl-allyloxy)-silane (351536-27-1)

Guidance literature:

Multi-step reaction with 5 steps

1: K₂CO₃ / acetone / Heating

2: DIBAL / 1 h / 0 °C

3: PDC / dimethylformamide / 1.5 h / 20 °C

4: CCl₃CO₂H / dimethylformamide / 20 °C

5: imidazole / dimethylformamide / 20 °C

With 1H-imidazole; dipyridinium dichromate; diisobutylaluminium hydride; potassium carbonate; trichloroacetic acid; In N,N-dimethyl-formamide; acetone;

DOI:10.1021/jo010068c

upstream raw materials:

tert-butyldimethylsilyl chloride

1,1,1-trichloro-4-o-tolyl-but-3-en-2-ol

(E)-3-(2-methylphenyl)acrylic acid

methyl (E)-3-(2-methylphenyl)-2-propenoate

Downstream raw materials:

1,1,1-trichloro-4-o-tolyl-but-3-en-2-ol