2-hydroxy-6,6-dimethylcyclohexanemethanol

Base Information

• Chemical Name: 2-hydroxy-6,6-dimethylcyclohexanemethanol
• CAS No.: 134312-39-3
• Molecular Formula: C₉H₁₈O₂
• Molecular Weight: 158.241
• Mol file: 134312-39-3.mol

Synonyms:2-hydroxy-6,6-dimethylcyclohexanemethanol

Chemical Property of 2-hydroxy-6,6-dimethylcyclohexanemethanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-hydroxy-6,6-dimethylcyclohexanemethanol

There total 1 articles about 2-hydroxy-6,6-dimethylcyclohexanemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-hydroxy-6,6-dimethylcyclohexanemethanol (134312-39-3)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1002/hlca.19520350729

Reference yield: 78.0%

2-hydroxy-6,6-dimethylcyclohexanemethanol (134312-39-3) + p-toluenesulfonyl chloride (98-59-9) → 3,3-dimethyl-2-((((4-methylphenyl)sulfonyl)oxy)methyl)cyclohexanol (134312-40-6)

Guidance literature:

With pyridine; for 120h;

DOI:10.1021/jo00014a032

Reference yield:

2-hydroxy-6,6-dimethylcyclohexanemethanol (134312-39-3) → 3,3-dimethyl-2-methylenecyclohexanone (134312-41-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / pyridine / 120 h

2: Jones reagent / acetone / 0.5 h / Ambient temperature

3: 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / 2 h

With pyridine; jones reagent; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetone; benzene;

DOI:10.1021/jo00014a032

Downstream raw materials:

3,3-dimethyl-2-((((4-methylphenyl)sulfonyl)oxy)methyl)cyclohexanol

3,3-dimethyl-2-methylenecyclohexanone

Toluene-4-sulfonic acid 2,2-dimethyl-6-oxo-cyclohexylmethyl ester