C₁₇H₁₂ClNO₃

Base Information

• Chemical Name: C₁₇H₁₂ClNO₃
• CAS No.: 868697-59-0
• Molecular Formula: C₁₇H₁₂ClNO₃
• Molecular Weight: 313.74
• Mol file: 868697-59-0.mol

Synonyms:C₁₇H₁₂ClNO₃

Chemical Property of C₁₇H₁₂ClNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₂ClNO₃

There total 3 articles about C₁₇H₁₂ClNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-benzeneacetic acid, methyl ester (42058-59-3) → C17H12ClNO3 (868697-59-0)

Guidance literature:

Multi-step reaction with 4 steps

1: ammonium hydroxide / water / 0 - 20 °C

2: potassium carbonate / DMF (N,N-dimethyl-formamide) / 20 °C

3: potassium tert-butylate / DMF (N,N-dimethyl-formamide) / 1 h / -10 - 20 °C

4: thionyl chloride / DMF (N,N-dimethyl-formamide); dichloromethane / 3 h / 20 °C

With thionyl chloride; potassium tert-butylate; potassium carbonate; ammonium hydroxide; In DMF (N,N-dimethyl-formamide); dichloromethane; water;

Reference yield:

benzyl bromide (100-39-0) → C17H12ClNO3 (868697-59-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / DMF (N,N-dimethyl-formamide) / 20 °C

2: potassium tert-butylate / DMF (N,N-dimethyl-formamide) / 1 h / -10 - 20 °C

3: thionyl chloride / DMF (N,N-dimethyl-formamide); dichloromethane / 3 h / 20 °C

With thionyl chloride; potassium tert-butylate; potassium carbonate; In DMF (N,N-dimethyl-formamide); dichloromethane;

Reference yield:

m-hydroxyphenylacetic acid (621-37-4) → C17H12ClNO3 (868697-59-0)

Guidance literature:

Multi-step reaction with 5 steps

1: sulfuric acid / 5 h / Heating / reflux

2: ammonium hydroxide / water / 0 - 20 °C

3: potassium carbonate / DMF (N,N-dimethyl-formamide) / 20 °C

4: potassium tert-butylate / DMF (N,N-dimethyl-formamide) / 1 h / -10 - 20 °C

5: thionyl chloride / DMF (N,N-dimethyl-formamide); dichloromethane / 3 h / 20 °C

With thionyl chloride; sulfuric acid; potassium tert-butylate; potassium carbonate; ammonium hydroxide; In DMF (N,N-dimethyl-formamide); dichloromethane; water;

upstream raw materials:

m-hydroxyphenylacetic acid

3-hydroxy-benzeneacetic acid, methyl ester

benzyl bromide

Downstream raw materials:

C₃₀H₂₁N₃O₄

C₃₁H₃₂N₃O₇P