4-acetylbenzenesulfonyl azide

Base Information

• Chemical Name: 4-acetylbenzenesulfonyl azide
• CAS No.: 75177-14-9
• Molecular Formula: C₈H₇N₃O₃S
• Molecular Weight: 225.228
• Mol file: 75177-14-9.mol

Synonyms:4-acetylbenzenesulfonyl azide

Chemical Property of 4-acetylbenzenesulfonyl azide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-acetylbenzenesulfonyl azide

There total 3 articles about 4-acetylbenzenesulfonyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-acetylbenzene-1-sulfonyl fluoride (455-25-4) → 4-acetylbenzenesulfonyl azide (75177-14-9)

Guidance literature:

With trimethylsilylazide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1055/s-0035-1561626

Reference yield: 76.0%

4-acetylbenzenesulfonamide (1565-17-9) → 4-acetylbenzenesulfonyl azide (75177-14-9)

Guidance literature:

With 3-azidosulfonyl-3H-imidazole-1-ium hydrogen sulfate; potassium carbonate; In water; isopropyl alcohol; at 20 ℃; for 18h;

DOI:10.1021/jo500553q

Reference yield:

4-ethylbenzenesulfonyl fluoride (455-20-9) → 4-acetylbenzenesulfonyl azide (75177-14-9)

Guidance literature:

Multi-step reaction with 2 steps

1: KMnO₄; Mg(NO₃)2; aqueous acetone

2: NaN₃

With magnesium(II) nitrate; potassium permanganate; sodium azide; acetone;

upstream raw materials:

4-acetylbenzene-1-sulfonyl fluoride

4-ethylbenzenesulfonyl fluoride

4-acetylbenzenesulfonamide

Downstream raw materials:

C₁₄H₂₃N₂O₅PS

Refernces

• 1、 Stevens, Marc Y.,Sawant, Rajiv T.,Odell, Luke R.. "Synthesis of sulfonyl azides via diazotransfer using an imidazole-1-sulfonyl azide salt: Scope and 15N NMR labeling experiments". . p. 4826 - 4831. Retrieved 2014/06/23.