methyl N-[(benzyloxy)carbonyl]alanylmethioninate

Base Information

Chemical Name:methyl N-[(benzyloxy)carbonyl]alanylmethioninate
CAS No.:62188-81-2
Molecular Formula:C₁₇H₂₄N₂O₅S
Molecular Weight:368.454
Hs Code.:
NSC Number:164074
DSSTox Substance ID:DTXSID80304058

Synonyms:62188-81-2;NSC164074;DTXSID80304058;AKOS024432385;NSC-164074;methyl N-[(benzyloxy)carbonyl]alanylmethioninate;methyl (2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}propanoyl)amino]-4-(methylthio)butanoate

Suppliers and Price of methyl N-[(benzyloxy)carbonyl]alanylmethioninate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of methyl N-[(benzyloxy)carbonyl]alanylmethioninate

Chemical Property:

Vapor Pressure:1.32E-13mmHg at 25°C
Boiling Point:583.5°Cat760mmHg
Flash Point:306.7°C
Density:1.199g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:368.14059304
Heavy Atom Count:25
Complexity:441

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC(CCSC)C(=O)OC)NC(=O)OCC1=CC=CC=C1

Technology Process of methyl N-[(benzyloxy)carbonyl]alanylmethioninate

There total 6 articles about methyl N-[(benzyloxy)carbonyl]alanylmethioninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10332-17-9,874219-77-9
Met-OMe

: C₂₅H₂₈ClN₃O₅

: 62188-81-2
Z-Ala-Met-OMe

Guidance literature:: With 4-methyl-morpholine; In dichloromethane; at 0 - 20 ℃; for 15h; Inert atmosphere;
DOI:10.15227/orgsyn.063.0175

Reference yield:

: 63-68-3,26062-47-5,58576-49-1
L-methionine

: 62188-81-2
Z-Ala-Met-OMe

Guidance literature:: Multi-step reaction with 2 steps

1: thionylchloride / 2 h / Heating

2: 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h / temperature: below 0 deg C

With thionyl chloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1016/S0040-4020(01)87839-X

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 62188-81-2
Z-Ala-Met-OMe

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 4N NaOH / 1.) ca. 5 deg C, 15 min 2.) ethyl acetate, Et₂O, 5 min

2: 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h / temperature: below 0 deg C

With sodium hydroxide; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1016/S0040-4020(01)87839-X