Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

Base Information

Chemical Name:Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester
CAS No.:1029395-39-8
Molecular Formula:C₃₁H₃₀Cl₂N₄O₆
Molecular Weight:625.508
Hs Code.:

Synonyms:Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

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Chemical Property of Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

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Technology Process of Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

There total 2 articles about Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1029395-37-6
Nα-(2,6-dichlorobenzoyl)-4-{6-(N-formyl-N-methylamino-methyl)-quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

: 80-48-8
methyl p-toluene sulfonate

: 1029395-39-8
Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 55 - 65 ℃; Product distribution / selectivity;

Reference yield:

: 1029395-67-2
Nα-(2,6-dichlorobenzoyl)-4-{2-ethoxycarbonyl-amino-5-(N-formyl-N-methylaminomethyl)benzoylamino}-L-phenylalanine isopropyl ester

: 80-48-8
methyl p-toluene sulfonate

: 1029395-39-8
Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; isopropyl alcohol; at 20 ℃; Product distribution / selectivity;

Reference yield: 95.0%

: 1029395-39-8
Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester

: 917885-96-2
Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-methylamino-methyl)-quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester hydrochloride

Guidance literature:: Nα-(2,6-dichlorobenzoyl)-4-{1-methyl-6-(N-formyl-N-methylaminomethyl)quinazoline-2,4[1H,3H]-dion-3-yl}-L-phenylalanine isopropyl ester; With acetyl chloride; isopropyl alcohol; at 10 ℃; for 1h;

In Isopropyl acetate; isopropyl alcohol; at 70 ℃; for 24h;