(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

Base Information

Chemical Name:(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol
CAS No.:259657-11-9
Molecular Formula:C₂₉H₃₇NO₆S₂
Molecular Weight:559.748
Hs Code.:

Synonyms:(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

Suppliers and Price of (2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

There total 2 articles about (2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 151915-07-0
N-ethyl-(2-mesitylene)sulfonamide

: (2R)-2-(benzyloxy)-O,O'-ditosyl-1,4-butanediol

: 259657-11-9
(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

Guidance literature:: N-ethyl-(2-mesitylene)sulfonamide; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

(2R)-2-(benzyloxy)-O,O'-ditosyl-1,4-butanediol; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Further stages.;
DOI:10.1021/jm990375z

Reference yield:

: 123394-80-9
(2S)-2-phenylmethoxybutane-1,4-diol

: 259657-11-9
(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 87 percent / pyridine

2.1: NaH / dimethylformamide / 0.5 h / 0 °C

2.2: 77 percent / dimethylformamide / 16 h / 20 °C

With pyridine; sodium hydride; In N,N-dimethyl-formamide; 1.1: Tosylation / 2.1: Metallation / 2.2: Substitution;
DOI:10.1021/jm990375z

Reference yield: 50.0%

: 161452-28-4
N,N'-bis(2,4,6-trimethylbenzenesulfonyl)-1,4-butanediamine

: 259657-11-9
(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol

: 259657-12-0
(3R,12R)-dibenzyloxy-N¹,N¹⁴-diethyl-N¹,N⁵,N¹⁰,N¹⁴-tetrakis(mesitylenesulfonyl)homospermine

Guidance literature:: N,N'-bis(2,4,6-trimethylbenzenesulfonyl)-1,4-butanediamine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

(2R)-2-(benzyloxy)-4-[N-(mesitylenesulfonyl)ethylamino]-O-tosyl-1-butanol; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Further stages.;
DOI:10.1021/jm990375z