N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine

Base Information

• Chemical Name: N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine
• CAS No.: 862124-46-7
• Molecular Formula: C₃₉H₅₃N₃O₉
• Molecular Weight: 707.865
• Mol file: 862124-46-7.mol

Synonyms:N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine

Chemical Property of N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine

There total 3 articles about N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-nitrophenyl-4'-hydroxymethylphenyl-1'-oxyallylacetate carbonate (192064-31-6) + N1,N9-bis-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl-norspermidine (674297-98-4) → N1,N9-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N5-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine (862124-46-7)

Guidance literature:

With dmap; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1039/b804771e

Reference yield:

2-acetyldimedone (1755-15-3) → N1,N9-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N5-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine (862124-46-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / ethanol / 2 h / Heating

2: 74 percent / dimethylformamide / 16 h

In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2005.04.039

Reference yield:

bis(3-aminopropyl)amine (56-18-8) → N1,N9-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N5-[4-(allyloxycarbonylmethoxy)benzyloxycarbonyl]norspermidine (862124-46-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / ethanol / 2 h / Heating

2: 74 percent / dimethylformamide / 16 h

In ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2005.04.039

upstream raw materials:

4-nitrophenyl-4'-hydroxymethylphenyl-1'-oxyallylacetate carbonate

N¹,N⁹-bis-1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl-norspermidine

bis(3-aminopropyl)amine

2-acetyldimedone

Downstream raw materials:

N¹,N⁹-bis[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N⁵-[4-(hydroxycarbonylmethoxy)benzyloxycarbonyl]norspermidine