674297-98-4Relevant articles and documents
Cationic lipids
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Page/Page column 22, (2014/07/07)
The invention provides a cationic lipid comprising: (i) one head group, comprising one or more amino acids, in which at least one amino acid has a side chain that comprises a cationic moiety or a cationic precursor;(ii) a linking moiety of formula (5): [i
Mechanism and structure-activity relationships of norspermidine-based peptidic inhibitors of trypanothione reductase
Dixon, Mark J.,Maurer, Richard I.,Biggi, Cristina,Oyarzabal, Julen,Essex, Jonathan W.,Bradley, Mark
, p. 4513 - 4526 (2007/10/03)
A library of polyamine-peptide conjugates based around some previously identified inhibitors of trypanothione reductase was synthesised by parallel solid-phase chemistry and screened. Kinetic analysis of library members established that subtle structural