Halofenozide

Base Information

• Chemical Name: Halofenozide
• CAS No.: 112226-61-6
• Deprecated CAS: 468062-58-0
• Molecular Formula: C18H19 Cl N2 O2
• Molecular Weight: 330.814
• Hs Code.: 29242990
• European Community (EC) Number: 431-600-4,601-173-0
• UNII: C81K20PELV
• DSSTox Substance ID: DTXSID4032619
• Nikkaji Number: J816.015E
• Wikidata: Q27117858
• Metabolomics Workbench ID: 55871
• ChEMBL ID: CHEMBL226969
• Mol file: 112226-61-6.mol

Synonyms:halofenozide;N'-benzoyl-4-chloro-N'-(2-methyl-2-propanyl)benzohydrazide;N-4-chlorobenzoyl-N'-benzoyl-N'-tert-butylhydrazine;RH-0345;RH0345

Chemical Property of Halofenozide

Chemical Property:

• Melting Point: 198.0-199.0°
• Boiling Point: °Cat760mmHg
• PKA: 10.41±0.46(Predicted)
• Flash Point: °C
• PSA: 49.41000
• Density: 1.205g/cm³
• LogP: 4.31660
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 330.1135055
• Heavy Atom Count: 23
• Complexity: 419

Purity/Quality:

99.9% ^*data from raw suppliers

Halofenozide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,N
• Hazard Codes: Xi,N
• Statements: 43-51/53
• Safety Statements: 24-37-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)N(C(=O)C1=CC=CC=C1)NC(=O)C2=CC=C(C=C2)Cl
• Uses: Halofenozide is a dibenzoylhydrazine based pesticide. Halofenozide is an ecdysteroid agonist used as white grub control. Halofenozide functions by interfering with the normal growth and development in insects. Insecticide. Halofenozide is a dibenzoylhydrazine based pesticide. Halofenozide is an ecdysteroid agonist used as white grub control. Halofenozide functions by interfering with the normal growth and development in insects.

Technology Process of Halofenozide

There total 2 articles about Halofenozide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-4,6-dimethoxy-1 ,3,5-triazine (3140-73-6) + N'-tert-butyl-N-(4-chlorobenzoyl)hydrazine (23875-76-5) → halofenozide (112226-61-6)

Guidance literature:

With 4-methyl-morpholine; benzoic acid; citric acid; In dichloromethane; acetonitrile;

Reference yield:

→ halofenozide (112226-61-6)

Guidance literature:

Reference yield: 85.0%

carbonochloridic acid, chloromethyl ester (22128-62-7) + halofenozide (112226-61-6) → N'-benzoyl-N'-tert-butyl-N-(4-chlorobenzoyl)hydrazine-carboxylic acid chloromethyl ester (353757-50-3)

Guidance literature:

halofenozide; With potassium tert-butylate; In tetrahydrofuran; for 1h;

carbonochloridic acid, chloromethyl ester; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1055/s-2002-19296

upstream raw materials:

2-chloro-4,6-dimethoxy-1 ,3,5-triazine

N'-tert-butyl-N-(4-chlorobenzoyl)hydrazine

Downstream raw materials:

N'-benzoyl-N'-tert-butyl-N-(4-chlorobenzoyl)hydrazine-carboxylic acid 1-chloroethyl ester

thiocarbonic acid O-[N'-benzoyl-N'-tert-butyl-N-(4-chlorobenzoyl)hydrazino-methyl] ester S-ethyl ester

N'-benzoyl-N'-tert-butyl-N-(4-chlorobenzoyl)hydrazine-carboxylic acid chloromethyl ester

2-(benzyloxy)-1-chloro-2-oxoethyl 2-benzoyl-2-tert-butyl-1-(4-chlorobenzoyl)hydrazinecarboxylate

Refernces

• 1、 -. "Process for the preparation of monoacylhydrazines using carboxylic acids". . . Retrieved 2008/06/13.
• 2、 -. "Turfgrass insecticides". . . Retrieved 2008/06/13.