2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

Base Information

Chemical Name:2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate
CAS No.:1217528-70-5
Molecular Formula:C₁₆H₁₉BrN₂O₃
Molecular Weight:367.242
Hs Code.:

Synonyms:2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

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Chemical Property of 2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

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Technology Process of 2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

There total 1 articles about 2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 5414-19-7
1,1'-oxybis(2-bromo-ethane)

: 56649-48-0
(R)-(+)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid

: 1217528-70-5
2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

Guidance literature:: (R)-(+)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid; With tetra(n-butyl)ammonium hydroxide; In methanol; dichloromethane; Inert atmosphere;

1,1'-oxybis(2-bromo-ethane); In acetonitrile; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/jlcr.1597

Reference yield: 66.0%

: 1217528-70-5
2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

: 1217528-64-7
2-(2-[⁽¹⁸⁾F]fluoroethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

Guidance literature:: With [KC₂₂₂]⁺¹⁸F^-; In N,N-dimethyl-formamide; acetonitrile; at 200 ℃; for 0.000555556h; Inert atmosphere; Microwave irradiation;
DOI:10.1002/jlcr.1597

Reference yield: 5.0%

: 1217528-70-5
2-(2-bromoethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

: 2-(2-fluoroethoxy)ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; N,N-dimethyl-formamide; at 130 ℃; for 3h; Inert atmosphere;
DOI:10.1002/jlcr.1597