3(2H)-benzoxazoleacetic acid, 6-chloro-2-oxo-

Base Information

Chemical Name:3(2H)-benzoxazoleacetic acid, 6-chloro-2-oxo-
CAS No.:19739-40-3
Molecular Formula:C₉H₆ClNO₄
Molecular Weight:227.604
Hs Code.:
Mol file:19739-40-3.mol

Synonyms:2-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)acetic acid

Suppliers and Price of 3(2H)-benzoxazoleacetic acid, 6-chloro-2-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)acetic acid
500mg
$ 315.00

Crysdot
2-(6-Chloro-2-oxobenzo[d]oxazol-3(2H)-yl)aceticacid 97%
1g
$ 320.00

Crysdot
2-(6-Chloro-2-oxobenzo[d]oxazol-3(2H)-yl)aceticacid 97%
5g
$ 904.00

American Custom Chemicals Corporation
(6-CHLORO-2-OXO-1,3-BENZOXAZOL-3(2H)-YL)ACETIC ACID 95.00%
5MG
$ 495.89

Total 4 raw suppliers

Chemical Property of 3(2H)-benzoxazoleacetic acid, 6-chloro-2-oxo-

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3(2H)-benzoxazoleacetic acid, 6-chloro-2-oxo-

There total 7 articles about 3(2H)-benzoxazoleacetic acid, 6-chloro-2-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.7%

: tert-butyl 2-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)acetate

: 19739-40-3
2-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)acetic acid

Guidance literature:: With water; trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 4h; Inert atmosphere;
DOI:10.1016/j.bmc.2014.08.031

Reference yield:

: 19932-84-4
6-chlorobenzo[d]oxazol-2(3H)-one

: 105-39-5
chloroacetic acid ethyl ester

: 19739-40-3
2-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)acetic acid

Guidance literature:: 6-chlorobenzo[d]oxazol-2(3H)-one; chloroacetic acid ethyl ester; With caesium carbonate; In N,N-dimethyl-formamide; at 60 ℃;

With lithium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; water; N,N-dimethyl-formamide; pH=1;

Reference yield:

: 28443-50-7
2-amino-5-chlorophenol

: 19739-40-3
2-(6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 4 h / Reflux

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 - 20 °C

3: trifluoroacetic acid; water / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere

With water; sodium hydride; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.bmc.2014.08.031