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Doxylamine succinate

Base Information Edit
  • Chemical Name:Doxylamine succinate
  • CAS No.:562-10-7
  • Deprecated CAS:7047-26-9,121367-03-1
  • Molecular Formula:C4H4O4*C17H24N2O
  • Molecular Weight:388.464
  • Hs Code.:2933399090
  • European Community (EC) Number:209-228-7
  • NSC Number:756752,74772
  • UNII:V9BI9B5YI2
  • DSSTox Substance ID:DTXSID7020552
  • NCI Thesaurus Code:C47501
  • RXCUI:23665
  • ChEMBL ID:CHEMBL1200392
  • Mol file:562-10-7.mol
Doxylamine succinate

Synonyms:doxylamine succinate

Suppliers and Price of Doxylamine succinate
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Doxylamine Succinate
  • 100mg
  • $ 403.00
  • TRC
  • Doxylamine Succinate
  • 50g
  • $ 415.00
  • TRC
  • Doxylamine Succinate
  • 10g
  • $ 155.00
  • TCI Chemical
  • Doxylamine Succinate
  • 25G
  • $ 85.00
  • TCI Chemical
  • Doxylamine Succinate
  • 5G
  • $ 28.00
  • Sigma-Aldrich
  • Doxylamine succinate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • 1 mL
  • $ 39.40
  • Sigma-Aldrich
  • Doxylamine succinate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material
  • 045-1ml
  • $ 38.20
  • Sigma-Aldrich
  • Doxylamine Succinate Pharmaceutical Secondary Standard; Certified Reference Material
  • 1g
  • $ 114.00
  • Sigma-Aldrich
  • Doxylamine succinate salt
  • 5g
  • $ 77.70
  • Sigma-Aldrich
  • Doxylamine for system suitability European Pharmacopoeia (EP) Reference Standard
  • $ 190.00
Total 143 raw suppliers
Chemical Property of Doxylamine succinate Edit
Chemical Property:
  • Appearance/Colour:white to light cream powder 
  • Melting Point:103 - 108oC 
  • Boiling Point:364.9 °C at 760 mmHg 
  • Flash Point:174.5 °C 
  • PSA:99.96000 
  • Density:1.043 g/cm3 
  • LogP:2.85910 
  • Storage Temp.:Refrigerator 
  • Solubility.:Very soluble in water, freely soluble in ethanol (96 per cent). 
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:7
  • Rotatable Bond Count:9
  • Exact Mass:388.19982200
  • Heavy Atom Count:28
  • Complexity:369
Purity/Quality:

99% *data from raw suppliers

Doxylamine Succinate *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn 
  • Hazard Codes:Xn,T,F 
  • Statements: 22-36/37/38-20/21/22-39/23/24/25-23/24/25-11 
  • Safety Statements: 26-36/37-45-16-7 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O
  • Uses H1 Histamine receptor antagonist. Antihistaminic; sedative; hypnotic. antihistaminic, hypnotic Doxylamine succinate salt has been used as a therapeutic drug to check developmental toxicity.
Technology Process of Doxylamine succinate

There total 3 articles about Doxylamine succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With pyrographite; In ethyl acetate; at 60 ℃; Temperature; Solvent;
Guidance literature:
Multi-step reaction with 3 steps
1.1: hydrogenchloride; magnesium; iodine / diethyl ether; water / 15 h / Reflux
2.1: sodium amide / 5,5-dimethyl-1,3-cyclohexadiene / 5 h / 140 °C / Reflux
2.2: 3.5 h / Reflux
3.1: acetone / 1 h / Reflux
With hydrogenchloride; iodine; sodium amide; magnesium; In 5,5-dimethyl-1,3-cyclohexadiene; diethyl ether; water; acetone;
Guidance literature:
Multi-step reaction with 3 steps
1.1: hydrogenchloride; magnesium; iodine / diethyl ether; water / 15 h / Reflux
2.1: sodium amide / 5,5-dimethyl-1,3-cyclohexadiene / 5 h / 140 °C / Reflux
2.2: 3.5 h / Reflux
3.1: acetone / 1 h / Reflux
With hydrogenchloride; iodine; sodium amide; magnesium; In 5,5-dimethyl-1,3-cyclohexadiene; diethyl ether; water; acetone;
Refernces Edit
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