Chemical Property of Doxylamine
Chemical Property:
- Melting Point:25°C
- Refractive Index:1.5486 (estimate)
- Boiling Point:364.9 °C at 760 mmHg
- PKA:pKa 9.20(H2O
t = 25
c = 0.002–0.01) (Uncertain);4.4 (Uncertain);9.2 (Uncertain)
- Flash Point:174.5 °C
- PSA：25.36000
- Density:1.043 g/cm3
- LogP:2.92330
- Storage Temp.:-20°C Freezer, Under inert atmosphere
- Solubility.:Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
- XLogP3:2.5
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:6
- Exact Mass:270.173213330
- Heavy Atom Count:20
- Complexity:276
- Purity/Quality:
-
99.9% *data from raw suppliers
(±)-Doxylamine *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Drug Classes:Antihistamines
- Canonical SMILES:CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C
- Recent ClinicalTrials:Pharmacokinetics and Bioequivalence of Doxylamine + Pyridoxine, Film-coated, Enteric-soluble Tablets, and Diclectin, Delayed Release Tablets, in Healthy Volunteers
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Uses
Antihistaminic. (±)-Doxylamine is an intermediate in the synthesis of Doxylamine N, N’-Dioxide (D562025), which is an impurity of Doxylamine (succinate salt, D562000), which is an H1 Histamine receptor antagonist.
