Technology Process of 2,2',2,3,3',3-hexahydroxy-4,4',4-<1,3,5-benzenetriyltris(methyleniminocarbonyl)>tris benzoic acid
There total 5 articles about 2,2',2,3,3',3-hexahydroxy-4,4',4-<1,3,5-benzenetriyltris(methyleniminocarbonyl)>tris benzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) sodium boranate, borontrifluoride etherate, 2.) cc.HCl / 1.) THF, room temperature, 3 d, than reflux, 4 d, 2.) THF, reflux, 4 h
2: 95 percent / triethylamine / N,N-dimethyl-acetamide / 4 h
3: 1.) BBr3, 2.) H2O / 1.) CH2Cl2, ice cooling, than room temperature overnight, 2.) CH2Cl2, ice cooling, 4 h
With
hydrogenchloride; sodium metaborate; boron trifluoride diethyl etherate; water; boron tribromide; triethylamine;
In
N,N-dimethyl acetamide;
DOI:10.1016/S0040-4020(01)87606-7
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 60 percent / NaOH / methanol; H2O / Heating
2: 90 percent / thionyl chloride / 0.5 h / Heating
3: 95 percent / triethylamine / N,N-dimethyl-acetamide / 4 h
4: 1.) BBr3, 2.) H2O / 1.) CH2Cl2, ice cooling, than room temperature overnight, 2.) CH2Cl2, ice cooling, 4 h
With
sodium hydroxide; thionyl chloride; water; boron tribromide; triethylamine;
In
methanol; N,N-dimethyl acetamide; water;
DOI:10.1016/S0040-4020(01)87606-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / triethylamine / N,N-dimethyl-acetamide / 4 h
2: 1.) BBr3, 2.) H2O / 1.) CH2Cl2, ice cooling, than room temperature overnight, 2.) CH2Cl2, ice cooling, 4 h
With
water; boron tribromide; triethylamine;
In
N,N-dimethyl acetamide;
DOI:10.1016/S0040-4020(01)87606-7
