S-(o-tolyl) 4-methylbenzenesulfonothioate

Base Information

• Chemical Name: S-(o-tolyl) 4-methylbenzenesulfonothioate
• CAS No.: 95493-62-2
• Molecular Formula: C₁₄H₁₄O₂S₂
• Molecular Weight: 278.396
• Mol file: 95493-62-2.mol

Synonyms:S-(o-tolyl) 4-methylbenzenesulfonothioate

Chemical Property of S-(o-tolyl) 4-methylbenzenesulfonothioate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of S-(o-tolyl) 4-methylbenzenesulfonothioate

There total 10 articles about S-(o-tolyl) 4-methylbenzenesulfonothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

p-toluene sulfinic acid (536-57-2) + 2-thiocresol (137-06-4) → S-(o-tolyl) 4-methylbenzenesulfonothioate (95493-62-2)

Guidance literature:

With lithium perchlorate; In acetonitrile; at 20 ℃; for 5h; Electrochemical reaction;

DOI:10.1002/adsc.201900047

Reference yield: 85.0%

toluene-4-sulfonic acid hydrazide (1576-35-8) + 2-thiocresol (137-06-4) → S-(o-tolyl) 4-methylbenzenesulfonothioate (95493-62-2)

Guidance literature:

With tert.-butylhydroperoxide; copper(ll) bromide; In acetonitrile; at 80 ℃; for 2h; Schlenk technique;

DOI:10.1021/acs.joc.7b01121

Reference yield: 82.0%

sodium 4-methylbenzenesulfinate (824-79-3) + 2-thiocresol (137-06-4) → S-(o-tolyl) 4-methylbenzenesulfonothioate (95493-62-2)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; ammonium tetrafluoroborate; oxygen; In N,N-dimethyl acetamide; water; at 30 ℃; for 18h;

DOI:10.1002/ejoc.201402847

upstream raw materials:

p-toluene sulfinic acid

2-methylbenzenesulfenyl chloride

sodium 4-methylbenzenesulfinate

2-thiocresol

Downstream raw materials:

N-(2-methylphenylsulfenyl)phthalimide

Refernces

• 1、 Huang, Cheng-Mi,Li, Jian,Wang, Shun-Yi,Ji, Shun-Jun. "TFA promoted multi-component reaction of aryldiazonium with sodium metabisulphite and thiols: Construction of thiosulfonate under transition-metal free conditions". supporting information. p. 1923 - 1926. Retrieved 2020/01/13.
• 2、 Zhang, Xiaofeng,Cui, Ting,Zhang, Yanghao,Gu, Weijin,Liu, Ping,Sun, Peipei. "Electrochemical Oxidative Cross-Coupling Reaction to Access Unsymmetrical Thiosulfonates and Selenosulfonates". . p. 2014 - 2019. Retrieved 2019/03/26.