Technology Process of C28H30O5
There total 12 articles about C28H30O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 1h;
- Guidance literature:
-
Methyltriphenylphosphonium bromide;
With
n-butyllithium;
In
tetrahydrofuran;
at 0 ℃;
for 2h;
C27H28O6;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 16.3333h;
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 °C
1.2: 2 h
2.1: acetic acid / 16 h / 20 °C
3.1: sodium periodate / 1,4-dioxane / 1.5 h / 20 °C
4.1: sodium hydroxide / water; tetrahydrofuran / 48 h / 20 °C / Cooling with ice
5.1: triethylamine / 16 h / 0 - 20 °C
6.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.75 h / -78 °C
6.2: 0.25 h / -78 °C
7.1: triphenylphosphine hydrobromide; n-butyllithium / tetrahydrofuran / 17 h / -78 - 20 °C
8.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 16 h / 20 °C
9.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C
With
sodium periodate; n-butyllithium; oxalyl dichloride; tetrabutyl ammonium fluoride; triphenylphosphine hydrobromide; sodium hydride; acetic acid; dimethyl sulfoxide; triethylamine; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
6.1: Swern Oxidation / 6.2: Swern Oxidation;
