(Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid

Base Information

Chemical Name:(Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid
CAS No.:5662-81-7
Molecular Formula:C14H15NO4S
Molecular Weight:293.3382
Hs Code.:
DSSTox Substance ID:DTXSID10417024

Synonyms:(Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid;AC1NSYNC;DTXSID10417024;SMSF0006746;CB10168;BIM-0007638.P001

Suppliers and Price of (Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid

Chemical Property:

Vapor Pressure:6.93E-13mmHg at 25°C
Boiling Point:549°C at 760 mmHg
Flash Point:285.8°C
Density:1.333g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:293.07217913
Heavy Atom Count:20
Complexity:399

Purity/Quality:: >99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C2N(CCS2)C(=O)C=CC(=O)O
Isomeric SMILES:COC1=CC=CC=C1C2N(CCS2)C(=O)/C=C\C(=O)O

Technology Process of (Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid

There total 6 articles about (Z)-4-[2-(2-methoxyphenyl)-1,3-thiazolidin-3-yl]-4-oxobut-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 223611-42-5,165729-83-9
S-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl)thioacetate

: 5662-81-7
3,6,9,16,19,22-hexaoxa-12,13-dithiatetracosane-1,24-diol

Guidance literature:: With oxygen; sodium methylate; In methanol; for 12h;
DOI:10.1002/chem.200204544

Reference yield: 91.0%

: 90952-27-5
2-(2-(2-(2-mercaptoethoxy)ethoxy)ethoxy)ethan-1-ol

: 5662-81-7
3,6,9,16,19,22-hexaoxa-12,13-dithiatetracosane-1,24-diol

Guidance literature:: With triethylamine; In water; for 168h;
DOI:10.1016/j.bmc.2011.11.049

Reference yield:

: 112-60-7
Tetraethylene glycol

: 5662-81-7
3,6,9,16,19,22-hexaoxa-12,13-dithiatetracosane-1,24-diol

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 12 h / 0 °C

2: 12 g / 12 h / 20 °C

3: 96 percent / butan-2-one / 2 h / Heating

4: 60 percent / glacial acetic acid / 0.17 h / 45 °C

5: 93 percent / NaOMe; atmospheric oxigen / methanol / 12 h

With pyridine; oxygen; sodium methylate; acetic acid; In methanol; butanone;
DOI:10.1002/chem.200204544