O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate

Base Information

Chemical Name:O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate
CAS No.:1003193-81-4
Molecular Formula:C₂₂H₂₉F₃N₄O₆S
Molecular Weight:534.557
Hs Code.:

Synonyms:O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate

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Chemical Property of O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate

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Technology Process of O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate

There total 1 articles about O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.25%

: 640772-88-9
2,2-difluoro-N-{[(5S)-3-(3-fluoro-4-piperazin-1-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide

: 111-77-3,95507-80-5
2-(2-methoxyethoxy)ethyl alcohol

: 6160-65-2
1,1'-Thiocarbonyldiimidazole

: 1003193-81-4
O-[2-(2-methoxyethoxy)ethyl]-4-[(4-(5S)-{[(difluoroacetyl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl)-2-fluorophenyl]piperazine-1-carbothioate

Guidance literature:: 2-(2-methoxyethoxy)ethyl alcohol; 1,1'-Thiocarbonyldiimidazole; In tetrahydrofuran; at 0 - 20 ℃; for 4.08333h;

2,2-difluoro-N-{[(5S)-3-(3-fluoro-4-piperazin-1-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide; With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In tetrahydrofuran; for 15h;