Metam

Base Information

• Chemical Name: Metam
• CAS No.: 144-54-7
• Molecular Formula: C2H5NS2
• Molecular Weight: 107.2
• Hs Code.: 2930909090
• European Community (EC) Number: 205-632-2
• UNII: OA1I97689K
• DSSTox Substance ID: DTXSID5043970
• Nikkaji Number: J9.912K
• Wikidata: Q16747480
• ChEMBL ID: CHEMBL1413694
• Mol file: 144-54-7.mol

Synonyms:carbathione;iron methyldithiocarbamate;magnesium (2:1) methyldithiocarbamate;metam sodium;metham sodium;methyldithiocarbamate;methyldithiocarbamate, ammonium salt;methyldithiocarbamic acid sodium salt;monopotassium methyldithiocarbamate;monosodium methyldithiocarbamate dihydrate;Nematin;sodium methyldithiocarbamate;Vapam

Chemical Property of Metam

Chemical Property:

• Vapor Pressure: 15.3mmHg at 25°C
• Melting Point: 163-166 °C
• Refractive Index: 1.588
• Boiling Point: 120.3 °C at 760 mmHg
• PKA: 4.63±0.60(Predicted)
• Flash Point: 26.6 °C
• PSA: 82.92000
• Density: 1.199 g/cm³
• LogP: 0.81140
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 106.98634151
• Heavy Atom Count: 5
• Complexity: 42.9

Purity/Quality:

99% ^*data from raw suppliers

METAM 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CNC(=S)S

Technology Process of Metam

There total 5 articles about Metam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-(N-Methylthiocarbamoyl)-L-cysteine (21844-99-5) → N-methyldithiocarbamic acid (144-54-7) + 2-oxo-propionic acid (127-17-3)

Guidance literature:

With potassium phosphate buffer; 1,4-dihydronicotinamide adenine dinucleotide; lactate dehydrogenase (Sigma Type II, from rabbit muscle); pyridoxal 5'-phosphate; at 25 ℃; Michaelis constant Km and maximum velocity Vmax determination;

Reference yield:

S-(N-Methylthiocarbamoil)-D-cysteine → N-methyldithiocarbamic acid (144-54-7) + 2-oxo-propionic acid (127-17-3)

Guidance literature:

With potassium phosphate buffer; 1,4-dihydronicotinamide adenine dinucleotide; lactate dehydrogenase (Sigma Type II, from rabbit muscle); pyridoxal 5'-phosphate; at 25 ℃; Michaelis constant Km and maximum velocity Vmax determination;

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + methylamine (74-89-5) → N-methyldithiocarbamic acid (144-54-7)

Guidance literature:

With ammonia; In ethanol; water; at 15 - 20 ℃;

DOI:10.3184/030823410X12628833270368

upstream raw materials:

methyl thioisocyanate

S-(N-Methylthiocarbamoyl)-L-cysteine

carbon disulfide

methylamine

Downstream raw materials:

4-methylthiosemicarbazide

sodium N-methyldithiocarbamate

S-methyl N-methyl dithiocarbamate

carbon disulfide

Refernces

• 1、 -. "N - alkyl dithiocarbamate and preparation and application thereof (by machine translation)". Paragraph 0024. . Retrieved 2020/11/12.
• 2、 Zou, Yan,Yu, Shichong,Li, Renwu,Zhao, Qingjie,Li, Xiang,Wu, Maocheng,Huang, Ting,Chai, Xiaoxun,Hu, Honggang,Wu, Qiuye. "Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates". . p. 366 - 374. Retrieved 2014/02/14.